supported by the National Natural Science Foundation of China(No.81571426,81170554);the Natural Science Foundation of Zhejiang Province,China(No.LY14H040012);Public Project for Technological Research and Social Development,the Science and Technology Plan of Zhejiang Province,China(No.2013C31066)
蛋白质棕榈酰化是指饱和十六碳的棕榈酸盐通过硫酯键或者酰胺键连接在蛋白质肽链的半胱氨酸上,属翻译后修饰,可影响蛋白质的相互作用、稳定性及定位等功能。热休克蛋白90(heat shock protein 90,Hsp90)是一种重要的分子伴侣,已证明其参...