National Natural Science Foundation of China(Grant No.81172992);the National Basic Research Program of China(973 Program,Grant No.2009CB930300);Innovation Team of Ministry of Education(Grant No.BMU20110263)
The purpose of this study was to investigate the potential antitumor efficacy of conjugated linoleic acid-paclitaxel (CLA-PTX) on B16-F10 melanoma cell line in vitro and in vivo. The in vitro cytotoxicity, apoptosis...
National Natural Science Foundation of China (Grant No.30873170);the National Basic Research Program of China(973 Program 2007CB935800 and 2009CB930300)
Mitochondria are increasingly recognized as important targets for tumor treatment because of their central roles in apoptotic pathways and cellular metabolism. Dichloroacetate (DCA), a low molecular weight mitochond...