the National Undergraduates Innovating Experimentation Project(Grant No.201310350015);the program of Natural Science Foundation of Zhejiang Province(No.Y2100248);the program of Science and Technology Department of Zhejiang Province(No.2009C33155);The program of Health Bureau of Zhejiang Province(No.2009A218);The program of Science and Technology Divison of Taizhou Municipality(No.102KY15);The program of Zhejiang Provincial Administration of Traditional Chinese Medicine(No.2011ZA113)~~