Chitosan derivative with glycyrrhetinic acid(GA),which was accumulated specifically in liver,was synthesized.By ion-crosslinking of TPP in GA-CTS solution,GA-CTS-TPP complex nanoparticles were obtained.The physicochem...
Started from the liver targeting compounds(glycyrrhizin,glycyrrhetinicacid,bile acid),six(amine-terminated) compounds were prepared via two-step reactions.The NMR experiments provided the direct evidence of the ex...