supported by grants from the Key Project of National Science and Technology Support Programme(2009BAI78B05);Deutsche Forschungsgemeinschaft(DFG)(KO4136/1-1);the Key Laboratory of Immune and Control Schistosomiasis and Key Subject Development Special Program of Hunan Province,P.R.China(YZ2010-27)
supported by the Major State Basic Research Development of China(2007CB513108);special program of Hunan11th five-year,P.R.China(2006SK1001);the Key Research Project of Hunan,P.R.China(2007-985-2)