Project supported by the Nationd Natural Science Foundation of China, № F3930230, and by China Medial Board of America, № 92-568 and 99-697.
To develop an analytical method for simultaneous quantification of 5-hydroxyomeprazole (5-OH-OP) and omeprazole sulfone (OPS), and explore whether omepra-zole (OP) is an appropriate phenotypic probe for CYP2C19 and CY...