Project supported by China Medical Board 92-568 and 99-697.
AIM: To constitute a method to determine the estradiol metabolites in human liver microsome in low concentration of estradiol. METHODS: Use high performance liquid chromatography after solvent extraction, evaporation,...
Project supported by the National Natural Science Foundation of China, № F39330230, and by China Medical Board of America, № 92-568 and 99-697.
To identify the cytochrome P450 isoforms involved in proguanil (PG) activation to cycloguanil (CG) in Chinese liver microsomes. METHODS: The kinetics of the CG formation from PG was determined in the liver microsomes ...
Project supported by the Nationd Natural Science Foundation of China, № F3930230, and by China Medial Board of America, № 92-568 and 99-697.
To develop an analytical method for simultaneous quantification of 5-hydroxyomeprazole (5-OH-OP) and omeprazole sulfone (OPS), and explore whether omepra-zole (OP) is an appropriate phenotypic probe for CYP2C19 and CY...