ANTIMALARIALS

作品数：19被引量：9H指数：2
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相关领域：医药卫生更多>>
相关作者：卢爱华黄松林欧阳冬生王伟周宏灏更多>>
相关机构：湖南医科大学更多>>
相关期刊：《Journal of Pharmaceutical Analysis》《Advances in Bioscience and Biotechnology》《Asian Pacific Journal of Tropical Biomedicine》《Chinese Journal of Integrative Medicine》更多>>
相关基金：国家自然科学基金更多>>
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Diagnosis and management of malaria in the intensive care unit
《Journal of Intensive Medicine》2024年第1期3-15,共13页George Akafity Nicholas Kumi Joyce Ashong 
Malaria is responsible for approximately three-quarters of a million deaths in humans globally each year.Most of the morbidity and mortality reported are from Sub-Saharan Africa and Asia,where the disease is endemic.I...
关键词：MALARIA Intensive care unit Severe malaria Antimicrobial resistance ANTIMALARIALS Artemisinin-based combination therapy 
Interactions of Aurein with Model Membranes and Antimalarials
《American Journal of Analytical Chemistry》2024年第2期72-98,共27页Anaif M. Alhewaitey Nsoki Phambu Naif M. Alhawiti 
Aurein is a cationic antimicrobial peptide, rich in phenylalanine residues. Although the peptide has been extensively studied, its mechanism of action is not fully understood and has not been established. This project...
关键词：Aurein Fluorescence DPPC SPM cholesterol DPPC-SPM-CHOL QUININE ANTIMALARIALS 
Availability of Antimalarial Medicines in Community Pharmacies of Lusaka District, Zambia: Implications on Compliance to Malaria Treatment Guidelines
《Pharmacology & Pharmacy》2023年第4期85-97,共13页Tadious Chimombe Steward Mudenda Stephen Bwalya Tamara N’gona Christabel Nang’andu Hikaambo Webrod Mufwambi Audrey Hamachila Simon Nkowani Busiku Hamainza 
Background: Malaria remains a major cause of morbidity and mortality in Zambia, affecting all levels of society, with children under the age of five and pregnant women being most at risk of serious illness. The availa...
关键词：ANTIMALARIALS Antimalarial Medicines AVAILABILITY Community Pharmacies Zambia 
Current and emerging trends in antimalarial drugs:a comprehensive review
《Drug Combination Therapy》2022年第4期8-24,共17页Seema Rohilla Ankur Rohilla Davinder Kumar 
Malaria is a ubiquitous tropical disease which occurs by the bite of malaria parasite of genus Plasmodium spp.The procurement and treatment of malaria depend on the cost and emergence of drug resistance,chemical compo...
关键词：MALARIA PLASMODIUM ANTIMALARIALS NANOCARRIERS 
Reaching the malaria elimination goal in Brazil:a spatial analysis and time-series study
《Infectious Diseases of Poverty》2022年第2期104-104,共1页Gabriel Zorello Laporta Maria Eugenia Grillet Sheila Rodrigues Rodovalho Eduardo Massad Maria Anice Mureb Sallum 
Background:Since 2015,the Global Technical Strategy(GTS)for Malaria 2016–2030 has been adopted by the World Health Organization(WHO)as a comprehensive framework to accelerate progress for malaria elimination in endem...
关键词：MALARIA Antimalarials therapeutic use Brazil ERADICATION Prevention and control POLICY 
Profiling of seminal antioxidant indices and sperm quality in Plasmodium bergheiinduced malarial mice treated with Phyllanthus amarus被引量：1
《Asian pacific Journal of Reproduction》2022年第2期84-92,共9页Williams Oshiegbu Chinwendu Obogheneophruhe Elu Innocent Onyesom 
Objective:To evaluate the antiplasmodial activity of Phyllanthus(P.)amarus crude ethanol leaf extract and its effects on semen quality in male BALB/c mice.Methods:A total of 36 adult mice were divided into six groups,...
关键词：MALARIA Sperm quality Phyllanthus amarus Seminal oxidative stress Seminal antioxidant markers ANTIOXIDANTS Ethanol extracts ANTIMALARIALS 
Protecting future antimalarials from the trap of resistance:Lessons from artemisinin-based combination therapy (ACT) failures
《Journal of Pharmaceutical Analysis》2021年第5期541-554,共14页Nekpen Erhunse Dinkar Sahal 
Having faced increased clinical treatment failures with dihydroartemisinin-piperaquine(DHA-PPQ),Cambodia swapped the first line artemisinin-based combination therapy(ACT)from DHA-PPQ to artesunate-mefloquine given tha...
关键词：Artemisinin resistance QUIESCENCE K13 mutations Non-K13 mutations Artemisinin-based combination therapy (ACT)failure Drugs in development Malaria eradication 
Design,synthesis,and biological evaluation of multiple targeting antimalarials被引量：1
《Acta Pharmaceutica Sinica B》2021年第9期2900-2913,共14页Yiqing Yang Tongke Tang Xiaolu Li Thomas Michel Liqin Ling Zhenghui Huang Maruthi Mulaka Yue Wu Hongying Gao Liguo Wang Jing Zhou Brigitte Meunier Hangjun Ke Lubin Jiang Yu Rao 
supported by the National Natural Science Foundation of China(81622042,81773567 and 31771455);National Key R&D Program of China(2018YFA0507300,2018ZX09711001,2020YFE0202200);Innovation Capacity Building Project of Jiangsu province(BM2020019);Shanghai Post-doctoral Excellence Program(2020469)
Malaria still threatens global health seriously today.While the current discoveries of antimalarials are almost totally focused on single mode-of-action inhibitors,multi-targeting inhibitors are highly desired to over...
关键词：Drug design Multiple targeting compounds Antimalarial inhibitors Mechanism of action Membrane proteins 
Declining responsiveness of childhood Plasmodium falciparum infections to artemisinin-based combination treatments ten years following deployment as first-line antimalarials in Nigeria
《Infectious Diseases of Poverty》2019年第4期96-97,共2页Akintunde Sowunmi Godwin Ntadom Kazeem Akano Folasade O.Ibironke Adejumoke I.Ayede Chimere Agomo Onikepe A.Folarin Grace O.Gbotosho Christian Happi Stephen Oguche Henrietta U.Okafor Martin Meremikwu Philip Agomo William Ogala Ismaila Watila Olugbenga Mokuolu Finomo Finomo Joy C.Ebenebe Nma Jiya Jose Ambe Robinson Wammanda George Emechebe Wellington Oyibo Francis Useh Temitope Aderoyeje Titilope M.Dokunmu Omobolaji T.Alebiosu Sikiru Amoo Oluwabunmi K.Basorun Olubunmi A.Wewe Chukwuebuka Okafor Odafe Akpoborie Bayo Fatunmbi Elsie O.Adewoye Nnenna M.Ezeigwe Ayoade Oduola 
Background:The development and spread of artemisinin-resistant Plasmodium falciparum malaria in Greater Mekong Subregion has created impetus for continuing global monitoring of efficacy of artemisinin-based combinatio...
关键词：Declining responsiveness Falciparum malaria Children Artemisinin-based combination treatment NIGERIA 
Comparative effects of parenteral antimalarials in Swiss albino mice after chronic exposure to Plasmodium berghei
《Animal Models and Experimental Medicine》2018年第3期235-241,共7页Sylvester Aghahowa Kenka Okolocha 
Mice are considered to be a similar model to humans in the pathogenesis of malaria. This study evaluates the effect of parenteral antimalarials on the spleen and liver of Swiss albino mice after chronic exposure to Pl...
关键词：ANTIMALARIALS mice PLASMODIUM BERGHEI 
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