Aurein is a cationic antimicrobial peptide, rich in phenylalanine residues. Although the peptide has been extensively studied, its mechanism of action is not fully understood and has not been established. This project...
financially funded by the National Key R&D Program of China(No.2019YFC1905500);National Natural Science Foundation of China(No.21922409);National Natural Science Foundation of China(No.22274109).
Researchers engrossed in enantioseparation keep seeking for versatile chiral separation selectors.This work proposes a concept of quasi-dual-chiral-channel(QDCC)enantioseparation platform,where the surface sequentiall...
Background: One of the deadliest parasite infections is malaria. A combination of quinine sulphate and doxycycline is another therapeutic option for malaria that is resistant to chloroquine and is anticipated to be ab...
Malaria is one of the world's major public health concerns and numerous medicinal plants are commonly used for treating malaria.Traditional health care uses medicinal plants widely,but no scientific documentation is a...
This work was undertaken to analyze intramolecular and intermolecular interactions of Manzamenones from natural bond orbitals (NBO method). For their use in the treatment of malaria, the results of these molecules are...
Introduction: Black water fever (BWF) is a complication of severe Plasmodium falciparum infection in hemolysis of erythrocytes into the bloodstream releasing the hemoglobin directly into the blood vessels and causes s...
Malaria is a real public health problem. It’s one of the pathologies that mobilize the scientific community. Resistance to existing treatments is the basis for the search for new treatments. Some molecules such as Ma...
It has been known since March 2013 that Artesunate is considered the gold standard treatment for severe malaria [1][2][3]. However, in our regions, the dru...
grants from the National Natural Science Foundation of China(No.81560222);the Guizhou Science and Technology Foundation(No.[2017]7187,and No.[2013]2043).
The present study aimed to explore the molecular mechanisms underlying the increase of nicotinamide adenine dinucleotide phosphate:quinine oxidoreductase 1(NQO1)and y-glutamylcysteine synthetase(γ-GCS)in brain tissue...
the University of Nantes and the“Centre National de la Recherche Scientifique”(CNRS)for the financial support;the“Ministère de l’Enseignement Supérieur et de la Recherche Scientifique de Cote d’Ivoire”for a grant
The fabrication of a fully bio-sourced adsorbent of Cd(Ⅱ)by covalent immobilization of quinine on cellulose paper is described.The double bond of commercially available quinine was converted to a terminal alkyne func...