funded by the Spanish Ministry of Science,Innovation and Universities(Project No.PID2023-148417OAI00);the Spanish Ministry of Science and Innovation and by the European Union through the Next Generation Funds(Project No.PLEC2021-008076);funded by the Junta de Castilla y León through the projects“VAP208P20”,“VA178P23”;the program“CLU-2019-01 and CL-EI-2021-05-iuFOR Unit of Excellence”;co-funded by the European Regional Development Fund;support from the European Union's Horizon Europe research and innovation programme under the MSCA agreement No.101068728;PhD fellowships funded by Junta de Castilla y León(Orden EDU/601/2020 and Orden EDU/1508/2020);a Juan de la Cierva postdoctoral fellowship funded by MCIU/AEI/10.13039/501100011033 and“NextGenerationEU”/PRTR(Spain)。
RNA interference(RNAi)-based control technologies are gaining popularity as potential alternatives to synthetic fungicides in the ongoing effort to manage plant pathogenic fungi.Among these methods,spray-induced gene ...
Traditional Chinese medicine(TCM)offers diverse therapeutic compounds but faces challenges like poor bioavailability and instability.Recent innovations in drug delivery systems,including nanotechnology-based drug deli...
supported in part by grants from the National Natural Science Foundation of China(No.81981340417 to L.S.,No.81973878 to H.Y.);the Foundation of Shanghai Municipal Commission of Science and Technology(No.21S21901700);the Foundation of Jiangsu CM Clinical Innovation Center of Degenerative Bone&Joint Disease(Jiangsu science and education of traditional Chinese medicine[2021]No.4).
Photodynamic therapy(PDT)has attracted considerable interest in tumor treatment due to its precise temporal and spatial control.However,the off-target effects of photosensitizers and the hypoxic tumor microenvironment...
support from the Basic and Applied Basic Research Foundation of Guangdong Province,China(No.2021A1515220001).
Silicon-based nanomaterials,known for their unique properties and favorable biocompatibility,significantly impact sectors like energy,electronics,and biomedicine.Recently,metalorganic frameworks(MOFs)have emerged as p...
The eye is one of the most delicate organs in the body,and glaucoma is considered to be a major cause of blindness.The unique and distinct architecture and physiology of the human eye continue to pose a major challeng...
National Key Research and Development Program of China,Grant/Award Number:2022YFA1105304;National Natural Science Foundation of China,Grant/Award Numbers:32201088,82273954;Natural Science Foundation of Jiangsu Province,Grant/Award Number:BK20210010;Fundings for Clinical Trials from the Affiliated Drum Tower Hospital,Medical School of Nanjing University,Grant/Award Number:2022-LCYJ-MS-16。
Several therapeutic drugs including heptamethine cyanine dye(IR-780),doxorubicin(DOX),and others have exhibited positive outcomes in the treatment of multiple myeloma(MM).However,curing MM is still hampered by undesir...
Parkinson’s disease(PD)poses a significant therapeutic challenge,mainly due to the limited ability of drugs to cross the blood-brain barrier(BBB)without undergoing metabolic transformations.Levodopa,a key component o...
supported by the National Natural Science Foundation of China (Nos. 82474087, 82274108);the Young Qihuang Scholar Program of Traditional Chinese Medicine of the State (No. 2022256);Jiangxi University of Chinese Medicine Science and Technology Innovation Team Development Program (No.CXTD22006);Jiangxi Province 2023 Graduate Innovation Special Fund Project (No. YC2023-S793)。
Essential oils(EOs) are natural, volatile substances derived from aromatic plants. They exhibit multiple pharmacological effects, including antibacterial, anticancer, anti-inflammatory, and antioxidant properties, wit...
supported by the National Natural Science Foundation of China(Nos.82003687,52203138);supported by the Jilin Scientific and Technological Development Program(No.20200201415JC);supported by the Finance Project of Jilin Province;China(Nos.2019SRCJ016,2020SCZT036)。
Osteoporosis is a disease of bone metabolism homeostasis imbalance with obvious bone loss,damage to bone microstructure,and increased risk of fracture.The occurrence and development of osteoporosis is related to the a...
supported by the Defense Threat Reduction Agency Joint Science and Technology Office for Chemical and Biological Defense(No.HDTRA1-21-1-0010);the National Institutes of Health(Nos.R21AI159492,and R21AI175904).
The continued development of clustered regularly interspaced short palindromic repeats(CRISPR)technology has the potential to greatly impact clinical medicine,particularly for disease diagnosis and treatment.Despite h...