NANOCARRIERS

作品数:146被引量:338H指数:9
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相关领域:医药卫生一般工业技术更多>>
相关作者:赵燕军姚远马永正徐培曹诗林更多>>
相关机构:天津大学香港理工大学华南理工大学北京大学更多>>
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相关基金:国家自然科学基金中国博士后科学基金国家重点基础研究发展计划北京市自然科学基金更多>>
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Spray-induced gene silencing to control plant pathogenic fungi:A step-by-step guide
《Journal of Integrative Plant Biology》2025年第3期801-825,共25页Sandra Mosquera Mireille Ginésy Irene Teresa Bocos-Asenjo Huma Amin Sergio Diez-Hermano Julio Javier Diez Jonatan Niño-Sánchez 
funded by the Spanish Ministry of Science,Innovation and Universities(Project No.PID2023-148417OAI00);the Spanish Ministry of Science and Innovation and by the European Union through the Next Generation Funds(Project No.PLEC2021-008076);funded by the Junta de Castilla y León through the projects“VAP208P20”,“VA178P23”;the program“CLU-2019-01 and CL-EI-2021-05-iuFOR Unit of Excellence”;co-funded by the European Regional Development Fund;support from the European Union's Horizon Europe research and innovation programme under the MSCA agreement No.101068728;PhD fellowships funded by Junta de Castilla y León(Orden EDU/601/2020 and Orden EDU/1508/2020);a Juan de la Cierva postdoctoral fellowship funded by MCIU/AEI/10.13039/501100011033 and“NextGenerationEU”/PRTR(Spain)。
RNA interference(RNAi)-based control technologies are gaining popularity as potential alternatives to synthetic fungicides in the ongoing effort to manage plant pathogenic fungi.Among these methods,spray-induced gene ...
关键词:dsRNA delivery dsRNA stability dsRNA uptake fungal plant pathogens NANOCARRIERS spray-induced gene silencing 
Enhancing bioavailability in traditional Chinese medicine: Exploring strategies for optimized therapeutic efficacy
《Natural Therapy Advances》2025年第1期55-69,共15页John Osilama Thomas Ifeoluwa Margaret Idowu Sunitha Ganesha Rudrapatna 
Traditional Chinese medicine(TCM)offers diverse therapeutic compounds but faces challenges like poor bioavailability and instability.Recent innovations in drug delivery systems,including nanotechnology-based drug deli...
关键词:traditional Chinese medicine bioavailability enhancers drug delivery NANOCARRIERS therapeutic efficacy 
Enhancing the therapeutic efficacy of photodynamic therapy in colon cancer based on an ECN-mediated targeted drug delivery strategy
《Nano Research》2025年第3期417-428,共12页Kai Wang Huihui Bian Tao Ye Fusheng Shang Chenxi Zhang Dagui Chen Li Su Heng Yin Liang Zhao 
supported in part by grants from the National Natural Science Foundation of China(No.81981340417 to L.S.,No.81973878 to H.Y.);the Foundation of Shanghai Municipal Commission of Science and Technology(No.21S21901700);the Foundation of Jiangsu CM Clinical Innovation Center of Degenerative Bone&Joint Disease(Jiangsu science and education of traditional Chinese medicine[2021]No.4).
Photodynamic therapy(PDT)has attracted considerable interest in tumor treatment due to its precise temporal and spatial control.However,the off-target effects of photosensitizers and the hypoxic tumor microenvironment...
关键词:NANOCARRIERS photodynamic therapy Escherichia coli Nissle 1917 targeted drug delivery cancer therapy 
Silicon-based metal-organic frameworks(SiMOFs)for immunogenic cell death in cancer therapy
《Nano Research》2025年第1期628-641,共14页Min Han Zishan Chen Shiying Zhou Zunde Liao Xiangting Yi Yao He Yiling Zhong Kam W.Leong 
support from the Basic and Applied Basic Research Foundation of Guangdong Province,China(No.2021A1515220001).
Silicon-based nanomaterials,known for their unique properties and favorable biocompatibility,significantly impact sectors like energy,electronics,and biomedicine.Recently,metalorganic frameworks(MOFs)have emerged as p...
关键词:silicon-based nanomaterials NANOCARRIERS immunogenic cell death antitumor immune responses 
A Comprehensive Review on Metal Nanoparticles Produced by Green Synthesis and Their Applications in Glaucoma Treatment
《Journal of Bio-X Research》2024年第4期214-234,共21页Aravinda Nalla Dibyalochan Mohanty 
The eye is one of the most delicate organs in the body,and glaucoma is considered to be a major cause of blindness.The unique and distinct architecture and physiology of the human eye continue to pose a major challeng...
关键词:glaucoma treatment ocular drug delivery low bioavailabili NANOTECHNOLOGY NANOCARRIERS metal nanoparticles green chemistry 
Biomimetic cell membrane decorated ZIF-8 nanocarriers with IR-780 and doxorubicin loading for multiple myeloma treatment
《Aggregate》2024年第6期332-339,共8页Guangtao Gao Junyi Che Peipei Xu Bing Chen Yuanjin Zhao 
National Key Research and Development Program of China,Grant/Award Number:2022YFA1105304;National Natural Science Foundation of China,Grant/Award Numbers:32201088,82273954;Natural Science Foundation of Jiangsu Province,Grant/Award Number:BK20210010;Fundings for Clinical Trials from the Affiliated Drum Tower Hospital,Medical School of Nanjing University,Grant/Award Number:2022-LCYJ-MS-16。
Several therapeutic drugs including heptamethine cyanine dye(IR-780),doxorubicin(DOX),and others have exhibited positive outcomes in the treatment of multiple myeloma(MM).However,curing MM is still hampered by undesir...
关键词:BIOMIMETIC bone marrow homing cell membrane drug delivery multiple myeloma PDT/PTT 
Improving treatment for Parkinson’s disease:Harnessing photothermal and phagocytosis-driven delivery of levodopa nanocarriers across the blood-brain barrier
《Asian Journal of Pharmaceutical Sciences》2024年第6期163-179,共17页Kaili Liang Li Yang Jiawei Kang Bo Liu Ding Zhang Liyan Wang Wei Wang Qing Wang 
Parkinson’s disease(PD)poses a significant therapeutic challenge,mainly due to the limited ability of drugs to cross the blood-brain barrier(BBB)without undergoing metabolic transformations.Levodopa,a key component o...
关键词:LEVODOPA Oxidative stress Blood-brain barrier Photothermal effect PHAGOCYTOSIS 
Natural-derived porous nanocarriers for the delivery of essential oils被引量:1
《Chinese Journal of Natural Medicines》2024年第12期1117-1133,共17页CHEN Hongxin SU Xiaoyu LUO Yijuan LIAO Yan WANG Fengxia HUANG Lizhen FAN Aiguo LI Jing YUE Pengfei 
supported by the National Natural Science Foundation of China (Nos. 82474087, 82274108);the Young Qihuang Scholar Program of Traditional Chinese Medicine of the State (No. 2022256);Jiangxi University of Chinese Medicine Science and Technology Innovation Team Development Program (No.CXTD22006);Jiangxi Province 2023 Graduate Innovation Special Fund Project (No. YC2023-S793)。
Essential oils(EOs) are natural, volatile substances derived from aromatic plants. They exhibit multiple pharmacological effects, including antibacterial, anticancer, anti-inflammatory, and antioxidant properties, wit...
关键词:Essential oils Natural-derived porous nanoclays Delivery Engineering strategies Application 
The size-switchable microspheres co-loaded with RANK siRNA and salmon calcitonin for osteoporosis therapy
《Chinese Chemical Letters》2024年第12期214-220,共7页Xueyan Zhang Jicong Chen Songren Han Shiyan Dong Huan Zhang Yuhong Man Jie Yang Ye Bi Lesheng Teng 
supported by the National Natural Science Foundation of China(Nos.82003687,52203138);supported by the Jilin Scientific and Technological Development Program(No.20200201415JC);supported by the Finance Project of Jilin Province;China(Nos.2019SRCJ016,2020SCZT036)。
Osteoporosis is a disease of bone metabolism homeostasis imbalance with obvious bone loss,damage to bone microstructure,and increased risk of fracture.The occurrence and development of osteoporosis is related to the a...
关键词:OSTEOPOROSIS RANK siRNA Salmon calcitonin NANOCARRIERS Size-switchable microspheres 
Viral and nonviral nanocarriers for in vivo CRISPR-based gene editing
《Nano Research》2024年第10期8904-8925,共22页Zhongyuan Guo Audrey T.Zhu Ronnie H.Fang Liangfang Zhang 
supported by the Defense Threat Reduction Agency Joint Science and Technology Office for Chemical and Biological Defense(No.HDTRA1-21-1-0010);the National Institutes of Health(Nos.R21AI159492,and R21AI175904).
The continued development of clustered regularly interspaced short palindromic repeats(CRISPR)technology has the potential to greatly impact clinical medicine,particularly for disease diagnosis and treatment.Despite h...
关键词:clustered regularly interspaced short palindromic repeats(CRISPR) in vivo gene editing NANOCARRIERS recombinant adeno-associated viruses(rAAVs) virus-like particle(VLP) lipid nanoparticle(LNP) 
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