Objective:To evaluate the antimalarial activity of the aqueous extract of Euphorbia(E.)cordifolia Elliot against Plasmodium(P.)berghei-infected mice.Methods:Thirty healthy Swiss mice were intraperitoneally inoculated ...
Department of Science & Technology, Science & Engineering Research Board (SERB), New Delhi, India, for the award of National Post-Doctoral fellowship program (PDF/2016/000496)
Objective: The present study deals with the investigation of antiplasmodial potential of leaf methanolic extract of Aegle marmelos, Aristolochia indica and Cassia auriculata against Plasmodium berghei(NK65)infected mi...
Objective:To compare the protective effects of chitosan-trypolyphosphate(CS-TPP) nanoparticle conjugated chloroquine(CQ) with effect of CQ alone on the reversal of splenic damages and induction of apoptosis.Methods:Di...
Mice are considered to be a similar model to humans in the pathogenesis of malaria. This study evaluates the effect of parenteral antimalarials on the spleen and liver of Swiss albino mice after chronic exposure to Pl...
Objective: To investigate the alteration of biochemical parameters during Plasmodium berghei ANKA (P. berghei ANKA) infection in mice. Methods: Male BALB/c mice were intraperitoneally inoculated with 1 × 107 parasiti...
funded through the scholarship from the College of Health Sciences,University of Kwa Zulu Natal granted to the first author
Objective: To report the influence of transdermal delivery of asiatic acid(AA) in Plasmodium berghei-infected Sprague Dawley rats on physicochemical changes, %parasitaemia and associated pathophysiology. Methods: A to...
Objective:To assess the in vivo antimalarial potential of various solvent extracts and fractions of Trema orientalis.Methods:In this study,the animal model of antimalarial activity was employed using Plasmodium berghe...
supported by National Natural Science Foundation of China(NSFC)(No.81471978)
Objective: To explore the effect of immunogenicity and immunizing protection of GAMA gene DNA vaccine, which was related with merozoite, ookinete and sporozoite invasion. Methods:Gene fragments were obtained using PCR...
Objective: To assess the effects of hot water leaf extract of Nauclea latifolia(N. latifolia) on antioxidant status, lipid peroxidation values and parasite levels in hepatic and brain tissue of experimental mice(BALB/...
supported and funded by the Department of Biomedical and Forensic Sciences of university of Cape Coast,Ghana
Objective: To investigate the effect of pre-existing Schistosoma haematobium(S. haematobium) infection on malaria disease severity.Methods: The study involved the use of twenty-i ve imprinting control region mice, i f...