“Meridian tropism” refers to the organ-specific biological action(s) produced by a Chinese herb following its oral administration, which is analogous to the concept of “bioavailability” in Western medicine. In thi...
Objective:To compare the protective effects of chitosan-trypolyphosphate(CS-TPP) nanoparticle conjugated chloroquine(CQ) with effect of CQ alone on the reversal of splenic damages and induction of apoptosis.Methods:Di...
Objective:To evaluated the immunomodulatory effect of BRP-4,an acidic polysaccharide from Basella rubra(B.rubra) L on the macrophage activity.Methods:Phagocytic activity was determined by the ingestion of Latex Beads-...
Aim: To investigate the immunomodulating activity of astragalosides, the active compounds from a traditional tonic herb Astragalus membranaceus Bge, and to explore the molecular mechanisms underlying the actions, foc...
Objective To investigate the effects of recombinant vaccine Bifidobacterium bifidum(Bb) pGEX-Sj14-3-3 on splenocyte apoptosis in BALB/c mice. Methods Ninety-six BALB/c mice were randomly divided into two groups accord...
Aim: To investigate how co-delivery of the gene encoding C-C chemokine ligand-19 (CCL-19) affected the systemic immune responses to an anti-caries DNA vaccine pClA-P in mice. Methods: Plasmid encoding CCL19-GFP fu...
This work was supported by a grant from the National Natural Science Foundation of China (No. 30500468).
Background The common y chain (γc) plays a critical role in regulating proliferation, differentiation, and apoptosis of peripheral T-cells. It was previously confirmed that blocking the yc signal can successfully i...
This study aimed to explore a pharmacological activity marker for quality assurance of Dendrobium species. The immunopotentiating activity in aqueous extracts prepared from four Dendrobium species, including D. offici...
Supported by the National Basic Research Program of China(No.2009CB521908);the National Natural Science Foundation of China(Nos.30470405, 30570864,30670477 and 30770493);the National Natural Science Fund for Distinguished Young Scholars of China(No.30325011)
Aquaporins(AQPs) are molecular water channels that play important physiological roles in fluid trans-porting organs. The expression and function of AQPs in the immune system are largely unknown. CD 11 (a-d)/CD18 i...
Supported by grant from Program for Innovative Ability of Key Teachers in Universities of Heilongjiang Province
AIM: To investigate the effect of donor splenocyte infusion combined with cyclosporine A (CsA) on rejection of rat small bowel transplantation (SBT). METHODS: Male Sprague-Dawley (SD) rats and female Wistar ra...