SPLENOCYTE

作品数:15被引量:47H指数:3
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相关领域:医药卫生农业科学更多>>
相关期刊:《Science Bulletin》《China Medical Abstracts(Internal Medicine)》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Pharmacological Investigation of “Meridian Tropism” in Three “Shen” Chinese Herbs
《Chinese Medicine》2019年第4期121-135,共15页Pou-Kuan Leong Hoi-Yan Leung Wing-Man Chan Kam-Ming Ko 
“Meridian tropism” refers to the organ-specific biological action(s) produced by a Chinese herb following its oral administration, which is analogous to the concept of “bioavailability” in Western medicine. In thi...
关键词:CODONOPSIS RADIX GINSENG RADIX Panacis Qinquifolii RADIX ATP-Generation Capacity SPLENOCYTE Proliferation 
Nano chloroquine delivery against Plasmodium berghei NK65 induced programmed cell death in spleen
《Asian Pacific Journal of Tropical Medicine》2018年第9期540-546,共7页Satyajit Tripathy Sourav Chattopadhyay Sandeep Kr.Dash Motlalepula G.Matsabisa Somenath Roy 
Objective:To compare the protective effects of chitosan-trypolyphosphate(CS-TPP) nanoparticle conjugated chloroquine(CQ) with effect of CQ alone on the reversal of splenic damages and induction of apoptosis.Methods:Di...
关键词:SPLENOCYTE Apoptosis NANO CHLOROQUINE PLASMODIUM BERGHEI Chitosan 
Immune stimulatory activity of BRP-4,an acidic polysaccharide from an edible plant,Basella rubra L.被引量:5
《Asian Pacific Journal of Tropical Medicine》2014年第11期849-853,共5页Hye-Jin Park 
Objective:To evaluated the immunomodulatory effect of BRP-4,an acidic polysaccharide from Basella rubra(B.rubra) L on the macrophage activity.Methods:Phagocytic activity was determined by the ingestion of Latex Beads-...
关键词:BRP-4 Phagocytic ACTIVITY Macrophage SPLENOCYTE proliferation IMMUNE stimunlatory 
Astragaloside II triggers T cell activation through regulation of CD45 protein tyrosine phosphatase activity被引量:20
《Acta Pharmacologica Sinica》2013年第4期522-530,共9页Chun-ping WAN Li-xin GAO Li-fei HOU Xiao-qian YANG Pei-lan HE Yi-fu YANG Wei TANG Jian-min YUE Jia LI Jian-ping ZUO 
Aim: To investigate the immunomodulating activity of astragalosides, the active compounds from a traditional tonic herb Astragalus membranaceus Bge, and to explore the molecular mechanisms underlying the actions, foc...
关键词:immunomodulating agent Astragalus membranaceus Bge astragaloside II CD45 PTPase LCK T cell SPLENOCYTE Src-familykinase IFN-γ IL-2 CYCLOPHOSPHAMIDE 
Dynamic observation of splenocyte apoptosis in mice immunized with recombinant vaccine Bifidobacterium bifidum pGEX-Sj14-3-3 of Schistosoma japonicum
《China Medical Abstracts(Internal Medicine)》2013年第1期17-18,共2页张宁 
Objective To investigate the effects of recombinant vaccine Bifidobacterium bifidum(Bb) pGEX-Sj14-3-3 on splenocyte apoptosis in BALB/c mice. Methods Ninety-six BALB/c mice were randomly divided into two groups accord...
关键词:immunized SCHISTOSOMA vaccine CONA stimulation cytes CYTOMETRY statistically body separated 
Co-delivery of cc119 gene enhances anti-caries DNA vaccine pCIA-P immunogenicity in mice by increasing dendritic cell migration to secondary lymphoid tissues被引量:2
《Acta Pharmacologica Sinica》2013年第3期432-440,共9页Yan-hong YAN Sheng-cai QI Ling-kai SU Qing-an XU Ming-wen FAN 
Aim: To investigate how co-delivery of the gene encoding C-C chemokine ligand-19 (CCL-19) affected the systemic immune responses to an anti-caries DNA vaccine pClA-P in mice. Methods: Plasmid encoding CCL19-GFP fu...
关键词:chemokine CCL19 DNA vaccination anti-caries DNA vaccine dendritic cell SPLENOCYTE IFN-y IL-4 STOMATOLOGY 
Combination of donor splenocyte transfusion with blockade of γc signal synergizes to inhibit alloreactive T-cell proliferation and induces apoptosis被引量:1
《Chinese Medical Journal》2011年第18期2874-2878,共5页ZHOU Qi CHANG Sheng LIN Xing-guang XIANG Fu-li CHEN Zhong-hua 
This work was supported by a grant from the National Natural Science Foundation of China (No. 30500468).
Background The common y chain (γc) plays a critical role in regulating proliferation, differentiation, and apoptosis of peripheral T-cells. It was previously confirmed that blocking the yc signal can successfully i...
关键词:common γ chain donor splenocytes transfusion tolerance murine model 
Immunopotentiating Activity of Dendrobium Species in Mouse Splenocytes被引量:1
《Chinese Medicine》2011年第3期103-108,共6页David T. W. Lau Michel K. T. Poon Hoi Yan Leung Kam Ming Ko 
This study aimed to explore a pharmacological activity marker for quality assurance of Dendrobium species. The immunopotentiating activity in aqueous extracts prepared from four Dendrobium species, including D. offici...
关键词:DENDROBIUM Offincalis Dendrobii CAULIS SPLENOCYTE PROLIFERATION Concanavalin A 
Remarkably Decreased CD11b Positive Splenocytes in Aquaporin 3-Null Mice
《Chemical Research in Chinese Universities》2010年第2期217-220,共4页ZHU Na QIAO Ying ZHANG Di WANG Wen-juan LIU Jia LIU Tian-zhou MA Tong-hui 
Supported by the National Basic Research Program of China(No.2009CB521908);the National Natural Science Foundation of China(Nos.30470405, 30570864,30670477 and 30770493);the National Natural Science Fund for Distinguished Young Scholars of China(No.30325011)
Aquaporins(AQPs) are molecular water channels that play important physiological roles in fluid trans-porting organs. The expression and function of AQPs in the immune system are largely unknown. CD 11 (a-d)/CD18 i...
关键词:AQUAPORIN SPLENOCYTE CD1 lb Flow cytometry 
Formation of microchimerism in rat small bowel transplantation by spienocyte infusion被引量:1
《World Journal of Gastroenterology》2006年第26期4166-4169,共4页Da-Xun Piao Tao Jiang Lian-Xin Liu An-Long Zhu Shao-Feng Jin Ying-Hui Guan 
Supported by grant from Program for Innovative Ability of Key Teachers in Universities of Heilongjiang Province
AIM: To investigate the effect of donor splenocyte infusion combined with cyclosporine A (CsA) on rejection of rat small bowel transplantation (SBT). METHODS: Male Sprague-Dawley (SD) rats and female Wistar ra...
关键词:MICROCHIMERISM Splenocyte infusion Immunologic tolerance Small bowel transplantation 
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