financially supported by the National Natural Science Fund for Distinguished Young Scholars(21925506);the National Natural Science Foundation of China(U21A20331 and 81903743);Ningbo S&T Innovation 2025 Major Special Programme(2018B10055);CAS Key Project of Frontier Science Research(QYZDBSSW-SYS030);Ningbo Natural Science Foundation(2021J192);Ningbo Key Scientific and Technological Project(2022Z117);Ningbo Public Welfare Science and Technology Planning Project(2021S149);ZBTI Scientific Research Innovation Team(KYTD202105)。
supported by National Cancer Institute (R01CA155086);the Wells Center for Pediatric Research, Riley Children Foundation;Jeff Gordon Children's Foundation;Healthcare Initiatives, Inc.;IU Simon Cancer Center;funded by grants from the National Natural Science foundation of China(Nos. 91529302 and 81472641);Key Projects in the National Science & Technology Pillar Program of China (No. 2014BA109B03)
Gastric cancer is a leading cause of cancer-related mortality worldwide, and options to treat gastric cancer are limited. Fluorouracil (SFu)-based chemotherapy is frequently used as a neoadjuvant or an adjuvant agen...