supported in part by grants from NIH(CA115414 to S.H.);American Cancer Society(RSG-08-135-01-CNE to S.H.)
The mammalian target of rapamycin (mTOR), a serine/threonine protein kinase, acts as a "master switch" for cellular anabolic and catabolic processes, regulating the rate of cell growth and proliferation. Dysregulation...