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Functional and molecular mechanism of intracellular pH regulation in human inducible pluripotent stem cells被引量:1
《World Journal of Stem Cells》2018年第12期196-211,共16页Shih-Chi Chao Gwo-Jang Wu Shu-Fu Huang Niann-Tzyy Dai Hsu-Kai Huang Mei-Fang Chou Yi-Ting Tsai Shiao-Pieng Lee Shih-Hurng Loh 
Supported by Ministry of Science and Technology Grants of Taiwan,No.MOST 106-2320-B-016-003-MY2(to Loh SH)and No.MOST 106-2314-B-016-037-MY3(to Tsai YT);National Defense Medical Center Grants of Taiwan,No.MAB-106-033(to Loh SH),No.MAB-105-043 and No.MAB-106-034(to Dai NZ);Teh-Tzer Study Group for Human Medical Research Foundation of Taiwan,No.A1061037 and No.A1061054(to Loh SH)
AIM To establish a functional and molecular model of the intracellular pH(pH_i) regulatory mechanism in human induced pluripotent stem cells(hiPSCs).METHODS hiP SCs(HPS0077) were kindly provided by Dr. Dai from the Tr...
关键词:MICROSPECTROFLUORIMETRY HUMAN induced pluripotent stem cells Na^+/H^+exchanger Na^+/HCO3^-cotransporter Cl^-/OH^-exchanger Cl^-/HCO3^-exchanger V-ATPase INTRACELLULAR buffering power INTRACELLULAR pH BCECF 
Osteosarcoma cell proliferation and migration are partly regulated by redox-activated NHE-1被引量:2
《Journal of Clinical & Translational Research2015年第3期40-51,共12页Hua Bai Guojing Chen Congwen Fang Xuekang Yang Sixun Yu Chunxu Hai 
This work was partially supported by National Natural Science Foundation of China(No.31200635).
Background:Osteosarcoma(OS)is the most common primary malignant bone tumor in children and adolescents.OS is associated with locally aggressive growth and high metastatic potential.The mechanisms that underlie these p...
关键词:OSTEOSARCOMA Na^+/H^+exchanger 1 reactive oxygen species proliferation MIGRATION 
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