A NOVEL β-THALASSEMIA MUTATION——DELETION OF 4bp (-AAAC)DOWNSTREAM FROM THE CAP SITE  

作　　者：徐永华 吴涤梵 彭素芬 张美兰 周霞娣 任兆瑞 黄淑帧 曾溢滔 

机构地区：[1]Shanghai Institute of Cell Biology, Academia Sinica, Shanghai 200031, PRC [2]Shanghai Institute of Medical Genetics, Shanghai Children's Hopital, Shanghai 200041, PRC

出　　处：《Chinese Science Bulletin》1991年第21期1846-1848,共3页

基　　金：This work was supported by NIH Research Grant HL-29623

摘　　要：β-Thalassemia is a common monogenic blood disorder, caused by the mutations in the β-globin locus. This letter reports a new type of β thalassemia mutation that we encountered during the investigation of the molecular lesions of this disease in different parts of China.

关 键 词：GLOBIN letter locus MUTATION A NOVEL DNA Polymerase BamHI DELETION PLASMID 

分 类 号：N[自然科学总论]