Polymyxins are a class of last-resort antibiotics used to treat infections caused by multidrug-resistant bacteria. Mobile resistance determinants for polymyxins, including mcr-1 to mcr-10 genes, have previously been r...
supported by the National Key Research and Development Program of China(2022YFC2303900);the major projects of the National Natural Science Foundation of China(22193064);the Science Foundation(2022SKLID303)of the State Key Laboratory of Infectious Disease Prevention and Control,China。
Objective Our study aimed to conduct genomic characterization of Salmonella strains carrying the blaNDM-1 gene in the intestinal tract of healthy individuals.The objectives were to underscore the importance of genomic...
approved by the Institutional Animal Care and Use Committee(IACUC)of the First Affiliated Hospital of Fujian Medical University(No.2023048).
Background:Despite significant advancements in the development of anticancer therapies over the past few decades,the clinical management of colorectal cancer remains a challenging task.This study aims to investigate t...
funded by the National Natural Science Foundation of China(32141002);the Postdoctoral Fellowship Program of CPSF under Grant,China(GZC20241939);the China Agriculture Research System of MOF and MARA(CARS-39-14).
Moellerella wisconsensis is proposed for a member of the family Enterobacteriaceae previously designated as Enteric Group 46.In 1984,the majority of the bacterial isolates(6/8,75%)had been identified in Wisconsin,USA(...
Supported by the National Natural Science Foundation of China(No.81873070)。
Objective To investigate the effect of low concentration of Wenyang Tonglin Decoction(WTD)on the binding conditions of R45 plasmid conjugative transfer under liquid phase conjugation and its mechanism.Methods Escheric...
supported by the National Natural Science Foundation of China(32172188);Science and Technology Cooperation Project of ZheJiang Province(2023SNJF058-3)。
Multidrug-resistant(MDR)Enterobacteriaceae critically threaten duck farming and public health.The phenotypes,genotypes,and associated mobile genetic elements(MGEs)of MDR Enterobacteriaceae isolated from 6 duck farms i...
Background: The accumulation of free radicals is linked to a number of diseases. Free radicals can be scavenged by antioxidants and reduce their harmful effects. It is therefore essential to look for naturally occurri...
partially funded by the Excellence Strategy of the German Federal and State Governments,the ERC-COG Gem Omics(101044142);the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)(Project Numbers LO 2314/1-1 and SBF 1101/3,C08)。
Protein-protein interactions and the formation of protein complexes play a central role in the regulation of virtually all aspects of life.The identification and characterization of interactions between proteins is th...
Background and Purpose: The reintroduction of colistin as a last resort treatment against multi-resistant Gram-negative bacilli, is currently challenged by the emergence of colistin-resistant bacteria. The aim of this...