乳酪蛋白源免疫调节肽  

Immunomodulating Peptides Derived from Milk Casein

作　　者：黎观红[1] 张杰[1] 乐国伟[1] 施用晖[1] 

机构地区：[1]江南大学食品学院,无锡214036

出　　处：《中国食品添加剂》2004年第6期54-58,共5页China Food Additives

摘　　要：酪蛋白是乳中最主要的蛋白质 ,除了提供氨基酸和能量的营养功能外 ,酪蛋白还是生物活性肽的重要来源。这些生物活性肽本身以非活性状态存在于蛋白质氨基酸序列之中 ,当用适当的蛋白酶进行体外水解或在胃肠道消化过程中以及食品加工过程中 ,它们的活性就被释放出来 ,并可作为生理功能的重要调节剂。大量证据表明乳酪蛋白中存在大量的免疫调节肽。本文对乳酪蛋白来源的免疫调节肽的序列结构及其对免疫系统的调节机能做一综述。Casein is the main protein in milk. Besides the major role to supply amino acids and energy, casein is also the important source of a range of biologically active peptides. These bioactive peptides are inactive within the sequence of parent protein and can be released during in vitro enzymatic proteolysis or in vivo gastrointestinal digestion or food processing, and thus may act as potential physiological modulators. There is now a substantial body of evidence to indicate that milk casein contains a number of immunomodulating peptides. The amino acids sequence of the immunomodulating peptides derived from milk casein and its regulatory effects on the immune system are reviewed in this paper.

关 键 词：免疫调节 乳酪 调节机能 体外 酪蛋白 胃肠道 免疫系统 生物活性肽 食品加工过程 蛋白酶 

分 类 号：TS252[轻工技术与工程—农产品加工及贮藏工程] R151.41[轻工技术与工程—食品科学与工程]