菊粉类果聚糖对血甘油三酯和总胆固醇的影响——系统评价初探  

Systematic review of the effects of inulin-type fructans on blood lipid profiles: a meta-analysis

作　　者：吴婷[1] 杨月欣[1] 张立实[2] 韩军花[1] 

机构地区：[1]中国疾病预防控制中心营养与食品安全所,北京100050 [2]四川大学华西公共卫生学院

出　　处：《卫生研究》2010年第2期172-176,共5页Journal of Hygiene Research

基　　金：国家"十一五"科技支撑计划项目(N..2006BAD27B01)

摘　　要：目的探讨菊粉类果聚糖对人群的降脂作用。方法通过检索Medline、EMbase等国际期刊数据库和相关出版物的参考文献,以血浆总胆固醇和甘油三酯水平为分析指标的人体随机对照试验进行系统评价。由两位评价者独立阅读相关文献并提取数据,只有文献质量达到要求的研究才被纳入评价。最后共纳入9项研究进行评价。结果与对照组相比,菊粉类果聚糖能显著降低高脂血症人群的血浆总胆固醇和甘油三酯水平,而对血脂正常者无明显作用。结论系统评价的结果表明每日随食物摄入菊粉类果聚糖17g/d对高血脂人群有良好的降血脂作用。To conduct a systematic review on the efficacy of inulin-type fructans on lowering blood lipids, randomized controlled intervention trials on the analysis of plasma total cholesterol and triacylglycerol resulted from the treatment of dietary inulin-type fructans were selected from international journal databases and reference lists of relevant publications. The data of trials were extracted and identified by two independent reviewers. Only the qualified ones were included and evaluated. The results of 9 studies included in the systematic review indicated that the total cholesterol and triacylglycerol of subjects with hyperlipidemia could be significantly decreased by dietary inulin-type fructans,whereas the effects were absent in normal subjects. Blood lipids of subjects with hyperlipidemia could be decreased significantly by foods enriched with 17g of inulin-type fructans per day.

关 键 词：菊粉 果聚糖 血脂 系统评价 Meta分析 

分 类 号：Q53[生物学—生物化学] R151.3[医药卫生—营养与食品卫生学]