N-酰化低聚壳聚糖抗氧化活性的研究  

Antioxidant activity of N-acyl chitosan oligosaccharide

作　　者：孙涛[1] 银旭红[1] 康永峰[1] 周冬香[1] 党培养[1] 

机构地区：[1]上海海洋大学食品学院,上海201306

出　　处：《食品工业科技》2010年第6期72-75,共4页Science and Technology of Food Industry

基　　金：上海市教育委员会科研项目(07zz134);上海市重点学科建设项目专项基金(T1102)

摘　　要：低聚壳聚糖经N-酰化改性得到N-琥珀酰低聚壳聚糖(NSCOS)和N-邻苯二甲酰低聚壳聚糖(NPCOS),取代度均为0.25,用红外对其结构进行表征,并考察了其对羟基自由基·OH、1,1-二苯基苦基苯肼自由基DPPH·的清除活性以及还原能力。结果表明:NPCOS对羟基自由基·OH的清除能力与COS相仿,NSCOS最差;COS、NSCOS和NPCOS对DPPH·的清除能力以及还原能力的大小顺序均为COS>NPCOS>NSCOS,这可能与氨基被取代以及取代基的性质有关。N-succinyl chitosan oligosaccharide （NSCOS） and N-phthaloyl chitosan oligosaccharide （NSCOS） with the same substituting degree （0.2.5） were synthesized by N-acylation of chitosan oligosaccharide. The structures were characterized by FIR spectra.Their antioxidant activities including the scavenging of hydroxyl radical （ · OH）, 1,1- Diphenyl-2- picrylhydrazyl radical （ DPPH · ） and reducing power were evaluated.The results showed that the scavenging activity of hydroxyl radical · OH of NPCOS was close to COS,the NSCOS showed the lowest scavenging effect on hydroxyl radical · OH ;the orders of COS, NPCOS and NSCQS＇ s scavenging effect on DPPH · and reducing power were COS 〉 NPCOS 〉 NSCOS.The results may be attributed to the fact that the amino group was substituted and the properties of the substituting groups.

关 键 词：低聚壳聚糖 N-酰化 抗氧化 

分 类 号：TS201.2[轻工技术与工程—食品科学]