纳他霉素高产菌株发酵罐发酵条件研究  

Study of Natamycin High-Yield Strains Fermenter Fermentation Condition

作　　者：魏宝东[1] 林雨舒[1] 

机构地区：[1]沈阳农业大学食品学院,辽宁沈阳110161

出　　处：《食品与生物技术学报》2010年第3期448-452,共5页Journal of Food Science and Biotechnology

基　　金：辽宁省教育厅科研项目(2008662)

摘　　要：考察溶氧量、补糖及pH值等因素对纳他霉素高产菌株发酵罐生产纳他霉素的影响。以摇瓶发酵结果为依据,确定了发酵罐发酵的最适条件为:控制溶氧在30%～35%,补糖控制在发酵液糖质量浓度约为2g/dL,在纳他霉素大量合成阶段,维持发酵液中的pH值在5.2～5.4。该发酵条件下纳他霉素产量从分批发酵的3.01g/L提高到5.32g/L。The effect of the nutrition and environmental conditions,including dissolved oxygen,pH,added sugar and other factors on Natamycin production by Streptomyce natalensis SY-4795 were careful investigated,and the optimum conditions listed as follows：the dissolved oxygen 30%～35%,the constant sugar concentration in fermentation broth keep at 2%,pH 5.2～5.4.With the optimum fermentation conditions,natamycin production increase 3.01 g/L to 5.32 g/L in batch fermentation.

关 键 词：纳他霉素 发酵罐 发酵条件 产量 

分 类 号：TQ920.1[轻工技术与工程—发酵工程]