微生物过氧化氢酶的发酵生产及其在纺织工业的应用  

Fermentation production of microbial catalase and its application in textile industry

作　　者：张东旭[1] 堵国成[1,2] 陈坚[2] 

机构地区：[1]江南大学工业生物技术教育部重点实验室,无锡214122 [2]江南大学食品科学与技术国家重点实验室,无锡214122

出　　处：《生物工程学报》2010年第11期1473-1481,共9页Chinese Journal of Biotechnology

基　　金：教育部新世纪优秀人才支持计划(No.NCET-07-0378);江苏省科技支撑计划(No.SBE200900022);国家杰出青年基金(No.20625619);国家重点基础研究发展计划(973计划)(No.2007CB714306)资助~~

摘　　要：微生物过氧化氢酶是一种重要的工业酶制剂,可以催化分解过氧化氢生成水和氧气。这一酶制剂在食品、纺织、医药等领域表现出广泛的应用潜力。生物工程和基因工程技术的进步推动了微生物过氧化氢酶的发酵生产。以下综述了微生物过氧化氢酶发酵生产的进展及其在纺织工业中的应用,同时讨论了微生物过氧化氢酶的发酵生产和纺织工业应用的未来趋势。Microbial catalase is an important industrial enzyme that catalyzes the decomposition of hydrogen peroxide to water and oxygen.This enzyme has great potential of application in food,textile and pharmaceutical industries.The production of microbial catalase has been significantly improved thanks to advances in bioprocess engineering and genetic engineering.In this paper,we review the progresses in fermentation production of microbial catalase and its application in textile industry.Among these progresses,we will highlight strain isolation,substrate and environment optimization,enzyme induction,construction of engineering strains and application process optimization.Meanwhile,we also address future research trends for microbial catalase production and its application in textile industry.Molecular modification（site-directed mutagenesis and directed revolution） will endue catalase with high pH and temperature stabilities.Improvement of catalase production,based on the understanding of induction mechanism and the process control of recombinant stain fermentation,will further accelerate the application of catalase in textile industry.

关 键 词：微生物过氧化氢酶 发酵 纺织 应用 

分 类 号：TQ925[轻工技术与工程—发酵工程] TS190.1