乌饭树树叶水提取物改善糖尿病小鼠血糖和血脂水平的研究  

Effect of Vaccinium bracteatum Thunb.leaves aqueous extract on blood glucose and plasma lipid levels in streptozotocin-induced diabetic mice

作　　者：王立[1] 张雪彤[2] 章海燕[1] 程素娇[1] 钱海峰[1] 张晖[1] 张英[3] 

机构地区：[1]江南大学食品学院,食品科学与技术国家重点实验室,江苏无锡214036 [2]无锡市第四人民医院,江苏无锡214062 [3]中国食品发酵工业研究院国家食品质量监督检验中心,北京100027

出　　处：《食品工业科技》2012年第5期363-365,共3页Science and Technology of Food Industry

基　　金：江苏省自然科学基金(BK2010146);江南大学自主科研青年基金项目(JUSRP11016)

摘　　要：以链脲佐菌素造模糖尿病小鼠为研究对象,对乌饭树树叶水提取物的降血糖和血脂作用进行了研究,并与二甲双胍的效果进行了比较。结果表明,虽然效果没有二甲双胍明显,但水提物对糖尿病小鼠的血糖和血脂有明显的改善作用。相对模型对照组,灌胃四周水提物后糖尿病小鼠的体重增加了61.0%,血糖降低了14.2%,血脂水平也得到了明显的改善。The hypoglycemic effects of Vaccinium bracteatum Thunb.leaves（VBTL） aqueous extract in streptozotocin-induced diabetic mice was studied.The aqueous extract of VBTL showed obviously hypoglycemic and hypolipidemic effects,but the effects were weaker than those of dimethylbiguanide.Compared with diabetic mice in model control group,body weights of aqueous extract group（AEG,diabetic mice treated with VBTL aqueous extract） were partly recovered.The BG levels of AEG were reduced 14.2%,and body weights were increased 61.0%.AEG had significantly lower（p0.05） TC or TG levels and similar HDL-cholesterol or LDL-cholesterol levels.In conclusion,research clearly indicated that the aqueous extract of VBTL possess a potential hypoglycemic effect in streptozotocin-induced diabetic mice.

关 键 词：乌饭树 糖尿病 水提取物 降糖作用 

分 类 号：TS201.4[轻工技术与工程—食品科学]