气相色谱串联质谱法测定禽肉中二氯二甲吡啶酚残留  

Determination of Clopidol Residues in Poultry Products by GC-MS/MS

作　　者：陈迪[1] 朱坚[1] 樊祥[1] 于瑞祥[2] 邓晓军[1] 韩丽[1] 郭德华[1] 伊雄海[1] 黄帆[2] 张欣[2] 

机构地区：[1]上海出入境检验检疫局,上海200135 [2]上海海洋大学食品学院

出　　处：《检验检疫学刊》2013年第1期25-28,共4页Journal of Inspection and Quarantine

基　　金：国家质检总局标准委标准制修订项目(2009B680r)

摘　　要：建立了气相色谱串联质谱法测定禽肉中二氯二甲吡啶酚残留量的方法。样品用甲醇提取,中性氧化铝柱净化;在碱性条件下,以吡啶催化,丙酸酐衍生;用气相色谱串联质谱仪测定,外标法定量。结果显示,以不含二氯二甲吡啶酚的鸡肉和鸡肝为检测样品,采用外加法在样品中分别添加3个不同浓度水平的二氯二甲吡啶酚,加标回收率为70.2%-93.6%,相对标准偏差为9.1%-10.2%,鸡肉中检测限为5.0μg/kg,鸡肝中检测限为10.0μg/kg,满足检测要求。方法选择性好,适合禽肉中二氯二甲吡啶酚残留量的测定。A method is presented for the determination of clopidol residue in poultry products by GC - MS/MS. Lopidol residue was extracted with methanol and cleaned - up through Al2 O3 column and derived with propanoic an-hydride under alkaline conditions using pyridine as catalyst. Quantification was achieved by GC - MS/MS. The coveries of clopidol in poultry products were in the range from 70.2% to 93.6% at three spiked levels in both chicken meat and chicken livers. The relative standard deviation （RSD） were less than 10.2%. The limit of quan-tity （LOQ） was 5. 0μg/kg in chicken meat and 10. 0μg/kg in chicken livers. The method without interference is selective and suitable for the determination and confirmation of clopidol residue in ：poultry products.

关 键 词：二氯二甲吡啶酚 气相色谱串联质谱法 鸡肉 鸡肝 检测 

分 类 号：O657.63[理学—分析化学]