承德地区480例咨询病例染色体检查及分析  

Analysis of chromosomal karyotypes of peripheral blood in 480 consult cases.

作　　者：李继秋[1] 胡向明[1] 孙淑敏[1] 

机构地区：[1]承德医学院附属医院优生遗传研究室,河北067000

出　　处：《中国优生与遗传杂志》2000年第4期46-47,共2页Chinese Journal of Birth Health & Heredity

摘　　要：通过对 480例咨询病例进行临床分类及染色体检查发现习惯性流产、畸胎、死胎分娩史、不孕症夫妇及智力低下患者等几种临床多见疾病中染色体异常率分别为 8.73 %、4.95 %、5 0 %、9.83%。习惯性流产的异常核型从平衡易位、标记额外小染色体及标记Y染色体为多 ,并且提示大Y也是该组中常见的一种异常类型。Chromosomal exmination and karyotypes analysis of peripheral blood in 480 consult cases were performed from Sept.1987 to Dec.1995.The results showed that the abnormality rates of chromosomal karyotpes in clinical common diseases were 8.73% in habital abortion,4.59% abnormal tetus and tetue death,9.83% anoesia and 50% sterility;the number of abnormal karyotypes,such as balanced translocation,extra small mark chromosome and mark Y chromosome were much more in babital abortion.We also put forward that the case of big Y chromosome was a common abnormal karyotype.

关 键 词：平衡易位 罗伯逊易位 额外小染色体 标记染色体 

分 类 号：R715[医药卫生—妇产科学]