深圳居民膳食壬基酚和辛基酚暴露的风险评估  

Dietary exposure and risk assessment of nonylphenol and octylphenol from the Shenzhen total diet

作　　者：柳春红[1,2] 王伟华[1] 褚玥[1] 张锦周[3] 赖玉婷[1] 孙远明[1,2] 黄薇[3] 

机构地区：[1]华南农业大学食品学院,广东广州510642 [2]华南农业大学广东省食品质量安全重点实验室,广东广州510642 [3]深圳市疾病预防控制中心营养与食品卫生科,广东深圳518055

出　　处：《中国环境科学》2013年第7期1316-1322,共7页China Environmental Science

基　　金：广东省自然科学基金项目(S2011010001045);广东省教育部科技部产学研结合项目(2012B090600005)

摘　　要：为了解深圳市居民壬基酚和辛基酚的膳食暴露水平并预测其风险,利用深圳总膳食研究采集的膳食调查数据及代表性膳食样品进行暴露评估:采用分层整群随机抽样方法,抽取深圳城市区和农村区的244户居民、853人进行家庭膳食调查,利用3d 24h回顾法和称重记账法采集食物消费量数据;同时,采用高效液相色谱-质谱分析手段检测膳食样品中的壬基酚和辛基酚含量;并用风险指数评估人群暴露风险.结果表明,深圳城市区、农村区、深圳市居民的壬基酚膳食暴露水平分别为89.7,128.9,116.2ng/(kg bw);辛基酚的暴露水平分别为42.7,35.3,39.3ng/(kg bw).深圳城市区、农村区、深圳市居民壬基酚膳食暴露的风险指数分别为0.02、0.03、0.02,辛基酚的风险指数均为0.0004.深圳市居民壬基酚的膳食暴露水平高于辛基酚,但两者的风险指数均远低于1,暴露风险在可接受范围之内.To assess dietary exposure to nonylphenol（NP） and octylphenol（OP） for Shenzhen population.The exposure assessment was carried out based on the diet survey and representative food samples from Shenzhen total diet study.853 residents from 244 households in Shenzhen were selected through multi-stage randomized cluster sampling.Food consumption data was collected by three 24-h recalls and weighting and recording method.High performance liquid chromatography-mass/mass（HPLC-MS/MS） with solid-phase extraction,liquid-liquid extraction method was established for determination of NP and OP in food samples.Risk index was used for estimating the human exposure risk.The total daily amount of NP intake from the foods in urban area,suburban area and the whole city were 89.7,128.9,116.2ng/（kg bw） respectively.The total daily amount of OP intake was 42.7ng/（kg bw） for urban area,35.3ng/（kg bw） for suburban area and 39.3 ng/（kg bw） for the whole city.For risk assessment,the risk indexes of NP for the residents of urban and suburban area and the whole city were 0.02,0.03 and 0.02 respectively,while the indexes of OP for the three were all 0.0004.NP exposure was higher than OP in Shenzhen population,but the risk indexes for the two were lower than 1.Thus,the amount of NP and OP intakes through the total diet were found to be at a relatively safe level.

关 键 词：壬基酚 辛基酚 总膳食研究 暴露 风险指数 

分 类 号：X56[环境科学与工程—环境工程] TS201.6[轻工技术与工程—食品科学]