肽-金属离子螯合物的研究进展  

Research progress in peptide-mineral ion complexes

作　　者：王子怀[1,2] 胡晓[1,3] 李来好[1] 杨贤庆[1] 郝淑贤[1] 吴燕燕[1] 陈胜军[1] 岑建伟 

机构地区：[1]中国水产科学研究院南海水产研究所,农业部水产品加工重点实验室,国家水产品加工技术研发中心,广东广州510300 [2]上海海洋大学食品学院,上海201306 [3]中国科学院南海海洋研究所,广东广州510301

出　　处：《食品工业科技》2014年第8期359-363,共5页Science and Technology of Food Industry

基　　金：国家自然科学基金(31301454);“十二五”国家科技支撑计划项目(2012BAD28B06);国家农业科技成果转化资金项目(2010GB23260577,2010GB2E000335);国家现代农业产业技术体系(CARS-49);广东省科技计划重点项目(2011A020102005);广东省海洋渔业科技推广专项(A201101C01);中央级公益性科研院所基本科研业务费专

摘　　要：肽-金属离子螯合物是一种由肽类物质与金属离子发生螯合反应后生成的具有环状结构的化合物,其具有多种特殊的生物活性。本文综述了目前国内外对肽-金属离子螯合物的制备工艺、螯合反应机理、螯合物的生物活性及其构效关系的研究现状,并对肽-金属离子螯合物的发展前景进行了展望。Peptide-mineral ion complex,which is a kind of cyclic compounds obtained from the chelating reaction between peptide and mineral ion,has some special biologic activities. The present paper gave a review about the preparation procedure of the compound and the related reaction mechanism of chelation which had been studied by researchers all over the world. Besides,some other crucial properties and biologic activities of peptide-mineral ion complex were also covered in this paper. In addition,structure-activity relationship and the prospect of application of peptide-mineral ion complex were reviewed,too.

关 键 词：肽 金属离子 螯合物 生物活性 

分 类 号：TS201.2[轻工技术与工程—食品科学]