亚硫酸氢钠、没食子酸丙酯阻断大鼠体内N－亚硝基脯氨酸的合成  

Inhibitory Effect of Sodium Bisulfite and Propyl Gallate on Endogenous Fonnation of N-nitrosoproline in Rats

作　　者：梁学军[1] 胡继繁[1] 吴宪忠 

机构地区：[1]北京医科大学

出　　处：《中国食品添加剂》1995年第3期10-13,共4页China Food Additives

摘　　要：以２４小时尿中Ｎ－亚硝基脯氨酸（ＮＰＲＯ）排泄量为指标，研究亚硫酸氢钠（ＮａＨＳＯ３）和没食于酸丙酯（ＰＧ）阻断大鼠体内Ｎ－亚硝基脯氨酸合成的作用。结果证明１７．５ｍｇＮａＨＳＯ３、５ｍｇＰＧ能有效地阻断４０μｍｏｌ脯氨酸和４０μｍｏｌ亚硝酸钠在大鼠体内合成ＮＰＲＯ，阻断率分别为９９．７８％和９２．９８％。Effect of sodium bisulfite(NaHSO3) and propyl galste (PG) on endogenous for-mation of N-nitrosoproline in rats was studied by using the amount of N-nitrosoproline (NPRO)excreted in the urine as an index. It was found that 17.5mg NaHSO_3 and 5mg PG inhibited NPRO fonnation in rdts from 40μmol L-proline and 40μ mol nitrite,the rates of inhibition were 99.78%,928%, respectively.

关 键 词：N-亚硝基化合物 没食子酸丙酯 亚硫酸氢钠 阻断剂 食品添加剂 亚硝化 

分 类 号：TS202.3[轻工技术与工程—食品科学]