Chronic pancreatitis:A diagnostic dilemma  

作　　者：Sinead N Duggan Hazel M NíChonchubhair Oladapo Lawal Donal B O’Connor Kevin C Conlon 

机构地区：[1]Department of Surgery,Trinity College Dublin,Centre for Pancreatico-Biliary Diseases,Trinity Centre for Health Sciences,Tallaght Hospital,24 Dublin,Ireland

出　　处：《World Journal of Gastroenterology》2016年第7期2304-2313,共10页世界胃肠病学杂志（英文版）

基　　金：an unrestricted educational grant from The Meath Foundation www.meathfoundation.com(in part,to Duggan SN);unrestricted research grant from Mylan(in part,to NíChonchubhair HM)

摘　　要：Typical clinical symptoms of chronic pancreatitis are vague and non-specific and therefore diagnostic tests are required, none of which provide absolute diagnostic certainly, especially in the early stages of disease. Recently-published guidelines bring much needed structure to the diagnostic work-up of patients with suspected chronic pancreatitis. In addition, novel diagnostic modalities bring promise for the future. The assessment and diagnosis of pancreatic exocrine insufficiency remains challenging and this review contests the accepted perspective that steatorrhea only occurs with > 90% destruction of the gland.Typical clinical symptoms of chronic pancreatitis are vague and non-specific and therefore diagnostic tests are required, none of which provide absolute diagnostic certainly, especially in the early stages of disease. Recently-published guidelines bring much needed structure to the diagnostic work-up of patients with suspected chronic pancreatitis. In addition, novel diagnostic modalities bring promise for the future. The assessment and diagnosis of pancreatic exocrine insufficiency remains challenging and this review contests the accepted perspective that steatorrhea only occurs with > 90% destruction of the gland.

关 键 词：Pancreatitis  CHRONIC Diagnosis Exocrinepancreatic INSUFFICIENCY PANCREATIC ENZYME replacementtherapy MALABSORPTION 

分 类 号：R576[医药卫生—消化系统]