以培养新药创制人才为导向的药物化学课程教学创新与实践  

Medicinal chemistry teaching innovation and practice for the cultivation of drug discovery talents

作　　者：张永强 李浩 李剑[1] 毛斐[1] 邓卫平[1] 马红梅[1] 

机构地区：[1]华东理工大学药学院,上海200237

出　　处：《中国医药导报》2017年第34期117-119,136,共4页China Medical Herald

基　　金：国家自然科学基金青年基金项目(21602060)

摘　　要：实现我国制药行业跨越式发展,迫切需要培养大量新药创制人才。药物化学是新药研发的源头学科,药物化学课程教学是培养新药创制人才的基本形式。本文针对目前高校药物化学教学中存在的弊端,通过拓展课外专题性教学、创新双轨教学模式和建立二维教学评价体系,系统阐述了新形势下,激发学科兴趣,传授新药设计技巧,培养新药创制思维的新策略。并对教学实践效果与需要注意的问题进行了初步分析。The fast-growing pharmaceutical industry of China calls for the cultivation of many qualified drug discovery talents urgently. The research of medicinal chemistry is the major driving force of drug discovery. Therefore, the corresponding course teaching represents main approach for the cultivation of drug discovery talents. Herein, three strategies against the problems in present college medicinal chemistry course teaching were demonstrated, including topic-based teaching extension, comprehensive teaching methods innovation and two-dimensional teaching evaluation. These strategies were initially proved efficient in motivating the students to learn more practical drug design skills and in developing the innovative thinking ability for drug discovery. Furthermore, the initial teaching practice outcome was evaluated and some constructive suggestions were thus presented accordingly.

关 键 词：新药创制人才 药物化学 专题性教学 双轨教学模式 二维评价体系 教学实践 

分 类 号：R914[医药卫生—药物化学]