Advance in Research on Anti-tumor Pharmacological Mechanism of Cryptotanshinone  

作　　者：Jiaru WANG Lingqi MENG Yi ZHANG Hao WANG Wanting XU Yang LIU Yu ZHANG Tong ZHANG Shinong WANG Yuqing ZHAI Yinghua LUO Chenghao JIN 

机构地区：[1]College of Life Science & Technology,Heilongjiang Bayi Agricultural University

出　　处：《Medicinal Plant》2018年第6期11-14,共4页药用植物：英文版

基　　金：Supported by Multigrain Production and Processing Characteristic Discipline Construction Project;Postdoctoral Scientific Research Foundation of Heilongjiang Province of China(LBH-Q13132)

摘　　要：Cryptotanshinone is a natural active ingredient extracted from traditional Chinese medicine Radix Salviae Miltiorrhizae.It has a variety of pharmacological effects,in addition to preventing and treating ischemic diseases,coronary artery disease Alzheimer's disease and fighting tumors.The anti-tumor effects are exerted through inhibiting tumor cell proliferation,inducing tumor cell apoptosis,inhibiting tumor metastasis and invasion,inhibiting angiogenesis and regulating reactive oxygen species levels.The studies on the anti-tumor activity and action mechanism of cryptotanshinone in recent years are reviewed in this article.Cryptotanshinone is a natural active ingredient extracted from traditional Chinese medicine Radix Salviae Miltiorrhizae.It has a variety of pharmacological effects,in addition to preventing and treating ischemic diseases,coronary artery disease Alzheimer's disease and fighting tumors.The anti-tumor effects are exerted through inhibiting tumor cell proliferation,inducing tumor cell apoptosis,inhibiting tumor metastasis and invasion,inhibiting angiogenesis and regulating reactive oxygen species levels.The studies on the anti-tumor activity and action mechanism of cryptotanshinone in recent years are reviewed in this article.

关 键 词：CRYPTOTANSHINONE ANTI-TUMOR CELL PROLIFERATION APOPTOSIS 

分 类 号：R[医药卫生]