Role of tumor-associated immune cells in prostate cancer:angel or devil?  

作　　者：Shui-Qing Wu Hao Su Yin-Huai Wang Xiao-Kun Zhao 

机构地区：[1]Department of Urology,The Second Xiangya Hospital,Central South University,Changsha 410011,China

出　　处：《Asian Journal of Andrology》2019年第5期433-437,共5页亚洲男性学杂志（英文版）

摘　　要：Prostate cancer is the most common malignancy in the reproductive system of older males.Androgen deprivation therapy(ADT)is an important treatment for prostate cancer patients?However,almost all prostate cancer patients unavoidably progress to the castration-resistant stage after ADT treatment.Recent studies have shown that tumor-associated immune cells play major roles in the initiation,progression,and metastasis of prostate cancer.Various phenotypes of tumor-associated immune cells have tumor-promoting or antitumor functions mediated by interacting with tumor cells.Here,we review the current knowledge of tumorassociated immune cells in prostate cancer.

关 键 词：IMMUNE tolerance prostate cancer TUMOR associated IMMUNE cells TUMOR MICROENVIRONMENT 

分 类 号：R73[医药卫生—肿瘤]