抗性淀粉改善肠道功能及糖脂代谢的研究进展  

Progress in the Effect of Resistant Starch on Improving Intestinal Function and Glycolipid Metabolism

作　　者：李颖 张欣[1] 杨佳杰 马向阳 侯俊财[1] 李艾黎[1] LI Ying;ZHANG Xin;YANG Jiajie;MA Xiangyang;HOU Juncai;LI Aili(School of Food Science,Northeast Agricultural University,Harbin 150030,China)

机构地区：[1]东北农业大学食品学院,黑龙江哈尔滨150030

出　　处：《食品科学》2020年第13期326-335,共10页Food Science

基　　金：“十三五”国家重点研发计划重点专项(2016YFD0400605)。

摘　　要：抗性淀粉是一类在小肠内不被消化吸收,在大肠中能被肠道菌群发酵利用的新型优质膳食纤维。近年来研究显示抗性淀粉参与调节肠道菌群平衡和促进短链脂肪酸的产生,有助于改善肠道通透性和减轻炎症反应,从而在一定程度上促进宿主肠道健康。此外,抗性淀粉在稳定血糖血脂、改善胰岛素敏感性、调节糖脂代谢相关基因的表达等方面也发挥重要作用。本文在总结国内外关于抗性淀粉对肠道健康及糖脂代谢的影响及其相关作用机制的基础上,展望其在糖尿病、结直肠癌等相关疾病的预防与治疗或膳食干预领域中的应用前景。Resistant starch, a new type of high quality dietary fiber, is not digested and absorbed in the small intestine but fermented by the microflora in the large intestine. In recent years, studies have shown that resistant starch is involved in regulating intestinal microfloral balance and promoting the production of short-chain fatty acids, thereby helping improve intestinal permeability and reduce inflammatory responses and consequently promoting host intestinal health to some extent. In addition, resistant starch also plays an important role in stabilizing blood glucose and lipid, improving insulin sensitivity, and regulating the expression of genes related to glucose and lipid metabolism. The present paper gives a summary of recent studies evaluating the effects of resistant starch on intestinal health and glucose and lipid metabolism as well as its underlying mechanism. Further, it discusses future prospects for the application of resistant starch in the prevention and treatment of diabetes, colorectal cancer and other related diseases or dietary intervention.

关 键 词：抗性淀粉 肠道菌群 短链脂肪酸 糖脂代谢 

分 类 号：TS236.9[轻工技术与工程—粮食、油脂及植物蛋白工程]