Expert consensus of the Chinese Association for the Study of Pain on ion channel drugs for neuropathic pain  

作　　者：Hong Xiao Ke Ma Dong Huang Xian-Guo Liu Tang-Hua Liu Qing Liu Guang-Zhao Liu Tao Song Wei Tao Da-Sheng Wu Yun-Xia Wang Xiao-Qiu Yang Xiao-Mei Zhang Hui Liu Yan-Qing Liu 

机构地区：[1]Department of Algology,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China [2]Department of Algology,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China [3]Department of Algology,The Third Xiangya Hospital of Central South University,Changsha 410013,Hunan Province,China [4]Department of Physiology and Pain Research Center,Sun Yat-Sen University,Guangzhou 510080,Guangdong Province,China [5]Department of Algology,The Third People's Hospital of Yibin,Yibin 644000,Sichuan Province,China [6]Department of Algology,The Affiliated T.C.M Hospital of Southwest Medical University,Luzhou 646000,Sichuan Province,China [7]Department of Algology,The Second Hospital of Hebei Medical University,Shijiazhuang 050000,Hebei Province,China [8]Department of Algology,The First Affiliated Hospital of China Medical University,Shenyang 110001,Liaoning Province,China [9]Department of Neurosurgery,Shenzhen University General Hospital,Shenzhen 518055,Guangdong Province,China [10]Department of Algology,The People's Hospital of Jilin Province,Changchun 130021,Jilin Province,China [11]Department of Algology,Hubei Third People’s Hospital of Jianghan University,Wuhan 430033,Hubei Province,China [12]Department of Algology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China [13]Department of Algology,The First Affiliated Hospital of Kunming Medical University,Kunming 650032,Yunnan Province,China [14]Department of Algology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China

出　　处：《World Journal of Clinical Cases》2021年第9期2100-2109,共10页世界临床病例杂志

基　　金：Supported by Sichuan Science and Technology Program,No.2018SZ0386。

摘　　要：Neuropathic pain(NPP)is a kind of pain caused by disease or damage impacting the somatosensory system.Ion channel drugs are the main treatment for NPP;however,their irregular usage leads to unsatisfactory pain relief.To regulate the treatment of NPP with ion channel drugs in clinical practice,the Chinese Association for the Study of Pain organized first-line pain management experts from China to write an expert consensus as the reference for the use of ion channels drugs.Here,we reviewed the mechanism and characteristics of sodium and calcium channel drugs,and developed recommendations for the therapeutic principles and clinical practice for carbamazepine,oxcarbazepine,lidocaine,bulleyaconitine A,pregabalin,and gabapentin.We hope this guideline provides guidance to clinicians and patients on the use of ion channel drugs for the management of NPP.

关 键 词：Ion channel drug Neuropathic pain Expert consensus Guideline GABAPENTIN CARBAMAZEPINE OXCARBAZEPINE Lidocaine Bulleyaconitine A PREGABALIN 

分 类 号：R741[医药卫生—神经病学与精神病学]