OXCARBAZEPINE

作品数：12被引量：51H指数：3
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Theoretical insights into the degradation mechanisms, kinetics and eco-toxicity of oxcarbazepine initiated by OH radicals in aqueous environments被引量：1
《Journal of Environmental Sciences》2023年第7期189-201,共13页Yanhui Sun Ming Li Mohammad Hassan Hadizadeh Lin Liu Fei Xu 
This work was supported by the Shandong Provincial Natural Science Foundation of China(No.ZR2021MB039);the National Natural Science Foundation of China(No.21607089);the Shandong Provincial Key Research and Development Program(Major Scientific and Technological Innovation Project)(No.2020CXGC011402).
As an anticonvulsant,oxcarbazepine(OXC)has attracted considerable attention for its potential threat to aquatic organisms.Density functional theory has been used to study the mechanisms and kinetics of OXC degradation...
关键词：OXCARBAZEPINE OH radicals Degradation mechanisms Kinetic calculation Eco-toxicity evaluation 
Expert consensus of the Chinese Association for the Study of Pain on ion channel drugs for neuropathic pain被引量：7
《World Journal of Clinical Cases》2021年第9期2100-2109,共10页Hong Xiao Ke Ma Dong Huang Xian-Guo Liu Tang-Hua Liu Qing Liu Guang-Zhao Liu Tao Song Wei Tao Da-Sheng Wu Yun-Xia Wang Xiao-Qiu Yang Xiao-Mei Zhang Hui Liu Yan-Qing Liu 
Supported by Sichuan Science and Technology Program,No.2018SZ0386。
Neuropathic pain(NPP)is a kind of pain caused by disease or damage impacting the somatosensory system.Ion channel drugs are the main treatment for NPP;however,their irregular usage leads to unsatisfactory pain relief....
关键词：Ion channel drug Neuropathic pain Expert consensus Guideline GABAPENTIN CARBAMAZEPINE OXCARBAZEPINE Lidocaine Bulleyaconitine A PREGABALIN 
Oxcarbazepine monotherapy in children with benign epilepsy with centrotemporal spikes improves quality of life被引量：11
《Chinese Medical Journal》2020年第14期1649-1654,共6页Wan-Ting Liu Xiu-Xian Yan Da-Zhi Cheng Han-Zi Zhang Ning Ding Ke-Ming Xu Xin-Lin Zhou Qian Chen 
This work was supported by the grants from the National Key Research and Development Program of China(Nos.2016YFC0905100 and 2016YFC1000504);the CAMS Innovation Fund for Medical Sciences(CIFMS)(No.2016-I2M-1-002);Beijing Municipal Science&Technology Commission(No.Z171100000417020).
Background:Benign epilepsy with centrotemporal spikes(BECTS)is the most common type of childhood idiopathic focal epilepsy.BECTS is associated with pervasive cognitive deficits and behavior problems.While seizures can...
关键词：EPILEPSY Cognition Psychosocial difficulties Cognitive function Benign epilepsy with centro-temporal spikes 
Oxcarbazepine for trigeminal neuralgia may induce lower extremity weakness: A case report被引量：3
《World Journal of Clinical Cases》2020年第5期922-927,共6页Hyun-Gul Song Francis Sahngun Nahm 
BACKGROUND Although few studies have reported hyponatremia due to carbamazepine or oxcarbazepine in patients with epilepsy,no study has investigated cases of carbamazepine-or oxcarbazepine-induced hyponatremia or unst...
关键词：Case report Drug-related side effects and adverse reactions HYPONATREMIA OXCARBAZEPINE Spinal stenosis Trigeminal neuralgia 
SCN9A Epileptic Encephalopathy Mutations Display a Gain-offunction Phenotype and Distinct Sensitivity to Oxcarbazepine被引量：3
《Neuroscience Bulletin》2020年第1期11-24,共14页Shuzhang Zhang Zhiping Zhang Yuan Shen Yudan Zhu Kun Du Jingkang Guo Yonghua Ji Jie Tao 
We are grateful to Prof.Ren Lai and Shilong Yang(Kunming Institute of Zoology,Chinese Academy of Sciences)for providing the pEZ-Lv206-hNav 1.7 plasmid.This work was supported by the National Natural Science Foundation of China(81603410,31571032,and 31771191);the Shanghai Municipal Commission of Health and Family Planning Foundation(20184Y0086);Innovation Program of Shanghai Municipal Education Commission(15ZZ063);the Research Project of Putuo Hospital,Shanghai University of Traditional Chinese Medicine(2016102A and 2016208A);a Project for Capacity Promotion of Putuo District Clinical Special Disease.
Genetic mutants of voltage-gated sodium channels(VGSCs)are considered to be responsible for the increasing number of epilepsy syndromes.Previous research has indicated that mutations of one of the VGSC genes,SCN9A(Nav...
关键词：Voltage-gated sodium channel SCN9A EPILEPSY Electrophysiological function OXCARBAZEPINE Sensitivity Introduction 
Effect of oxcarbazepine on immune function, thyroid function and related factors in epilepsy patients
《Journal of Hainan Medical University》2019年第3期48-51,共4页Chun-Yu Yu Nuan Wang Hao Zhou Hong-Li Huang Shu-Chong Shan 
Objective: To investigate the effects of oxcarbazepine on immune function, thyroid function and related factors in epilepsy patients. Method: 90 patients with epilepsy who visited our hospital from January 2015 to May...
关键词：OXCARBAZEPINE EPILEPSY Immune FUNCTION THYROID FUNCTION Cytokines 
Oxcarbazepine oral suspension in young pediatric patients with partial seizures and/or generalized tonic-clonic seizures in routine clinical practice in China: a prospective observational study被引量：2
《World Journal of Pediatrics》2018年第3期280-289,共10页Jiong Qin Yi Wang Xin-Fang Huang Yu-Qin Zhang Fang Fang Yin-Bo Chen Zhong-Dong Lin Yan-Chun Deng Fei Yin Li Jiang Ye Wu Xiang-Shu Hu 
Background This study aimed to assess efficacy and safety of oxcarbazepine (OXC) oral suspension in pediatric patients aged 2-5 years with partial seizures (PS) and/or generalized tonic-clonic seizures (GTCS) in real-...
关键词：ANTIEPILEPTIC DRUGS Generalized tonic-clonic seizures OXCARBAZEPINE oral suspension Partial seizures PEDIATRIC patients 
Effect of voltage-gated sodium channels blockers on motility and viability of human spermin vitro
《Asian pacific Journal of Reproduction》2018年第2期62-71,共10页Hammad Ahmad Gakhar Ishrat Waheed Taseer Ahmad Naeem-ur-rahman 
Objective:To test the effect of voltage-gated sodium channels (VGSCs) blockers on the motility and viability of human spermin-vitro and to evaluate the tested compounds as potential contact spermicidal.Methods: Sperm ...
关键词：Human sperm VGSCs BLOCKERS Amiodarone PROCAINAMIDE and DISOPYRAMIDE CARBAMAZEPINE OXCARBAZEPINE PHENYTOIN 
Oxcarbazepine oral suspension in pediatric patients with partial seizures and/or generalized tonic-clonic seizures: a multi-center, single arm, observational study in China被引量：3
《World Journal of Pediatrics》2017年第6期551-559,共9页Yi Wang Yin-Bo Chen Yu-Qin Zhang Rong Luo Hua Wang Jun-Lan Lv Dong Wang Sui-Qiang Zhu Zhong-Dong Lin Jiong Qin 
Background:To assess efficacy and safety of oxcarbazepine (OXC) oral suspension in pediatric patients aged 2-16 years with partial seizures (PS) and/or generalized tonic-clonic seizures (GTCS) in real-world clinical p...
关键词：children efficacy generalized tonic-clonic seizures OXCARBAZEPINE ORAL SUSPENSION partial seizures 
Effect of Oxcarbazepine on serum inflammatory factors, intercellular adhesion molecule 1 and immune function in epileptic被引量：1
《Journal of Hainan Medical University》2017年第11期141-144,共4页Jie Yuan Jiang-Li Song Hong Zhang Shu-Qi Yu 
Objective:To study effect of Oxcarbazepine on serum inflammatory factors, intercellular adhesion molecule 1(ICAM-1) and immune function in epileptic.Methods: Selected 95 patients who were diagnosed as epileptic into t...
关键词：EPILEPSY OXCARBAZEPINE INFLAMMATORY factor ICAM-1 IMMUNE function 
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