PROCAINAMIDE

作品数:12被引量:17H指数:2
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相关领域:医药卫生更多>>
相关作者:徐智李青曹宏宇郭治彬单春文更多>>
相关机构:江西医学院第一附属医院中国人民解放军第一军医大学更多>>
相关期刊:《Asian pacific Journal of Reproduction》《Journal of Chemistry and Chemical Engineering》《Journal of Chinese Pharmaceutical Sciences》《Journal of Pharmaceutical Analysis》更多>>
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Effect of voltage-gated sodium channels blockers on motility and viability of human spermin vitro
《Asian pacific Journal of Reproduction》2018年第2期62-71,共10页Hammad Ahmad Gakhar Ishrat Waheed Taseer Ahmad Naeem-ur-rahman 
Objective:To test the effect of voltage-gated sodium channels (VGSCs) blockers on the motility and viability of human spermin-vitro and to evaluate the tested compounds as potential contact spermicidal.Methods: Sperm ...
关键词:Human sperm VGSCs BLOCKERS Amiodarone PROCAINAMIDE and DISOPYRAMIDE CARBAMAZEPINE OXCARBAZEPINE PHENYTOIN 
Investigation of binding behaviour of procainamide hydrochloride with human serum albumin using synchronous,3D fluorescence and circular dichroism被引量:4
《Journal of Pharmaceutical Analysis》2017年第2期103-109,共7页Kirthi Byadagi Manjunath Meti Sharanappa Nandibewoor Shivamurti Chimatadar 
Interaction of procainamide hydrochloride(PAH) with human serum albumin(HSA) is of great significance in understanding the pharmacokinetic and pharmacodynamic mechanisms of the drug. Multi-spectroscopic techniques...
关键词:Procainamide hydrochloride Human serum albumin Circular dichroism Synchronous fluorescence 3D fluorescence 
Differential Electrolytic Potentiometric, a Detector for FIA Determination of Procainamide in Pharmaceutical Preparations
《Journal of Chemistry and Chemical Engineering》2010年第12期7-12,共6页Safwan Mohammad Fraihat Abdulla Mohammad Abulkibash 
Differential electrolytic potentiometry (DEP) was coupled with Flow injection analysis (FIA) technique for the determination of Procainamide in pharmaceutical preparations. Platinum electrodes were used as an indi...
关键词:Differential electrolytic potentiometry flow injection analysis PROCAINAMIDE oxidation. 
Antiarrhythmic Efficacy of Neferine Assessed by Programmed Electrical Stimulation in a Canine Model of Electropharmacology被引量:6
《Journal of Chinese Pharmaceutical Sciences》2002年第2期35-42,共8页郭治彬 李青 曹宏宇 徐智 
An ishemic ventricular tachyarrhythmias canine model was established in open-chest dogs subjected to programmed electrical stimulation (PES)for 5-8 days after acute myocardial infarction. The electrophysiologic effect...
关键词:NEFERINE PROCAINAMIDE ARRHYTHMIA Ischemic ELECTROPHYSIOLOGY Myocardial infarction CANINE 
Electrophysiologic-electropharmacologic Method for Evaluating the Effects of Antagonizing Ventricular Tachyarrhythmic Drugs被引量:3
《Journal of Chinese Pharmaceutical Sciences》2002年第1期46-50,共5页郭治彬 李青 曹宏宇 徐智 
Objective To establish a canine model of electrophysiologic - electropharmacology as assessed by programmed electrical stimulation (PES),and to observe the electrophysiologic effects of Procainamide(PA) on normal and...
关键词:PROCAINAMIDE ARRHYTHMIA Ischemic ELECTROPHYSIOLOGY Myocardial infarction 
Effects of procainamide on 0morphological parameter of dense granule and a granule in blood platelet
《Journal of Medical Colleges of PLA(China)》1999年第2期144-148,共5页林继红 单春文 杨素勤 刘连璞 顾为望 
Objective: To study the protective effect of procainamide (PA) on the ultrastructure of blood platelets.Methods:The stereology measurement was used to study the effects of PA on morphological parameters of dense granu...
关键词:PROCAINAMIDE arachidonic acid BLOOD PLATELET electron MICROSCOPY STEREOLOGY measllrement 
Effect of procainamide on ultrastructure of blood platelet in rabbits被引量:2
《中国药理学报》1998年第4期376-379,共4页刘连璞 单春文 柳息洪 肖涣才 杨淑琴 
EfectofprocainamideonultrastructureofbloodplateletinrabbitsLIULianPu,SHANChunWen1,2,LIUXiHong,XIAOHuanCa...
关键词:普鲁卡因胺 血小板聚集 超微结构 
Effects of procainamide on adenosine diphosphate-induced platelet aggregation and thromboxane B_2 production in rabbits in vitro
《Journal of Medical Colleges of PLA(China)》1998年第3期202-204,共3页单春文 林继红 金云海 
Turbidimetry and radioimmunoassay were used to study the effects of procainamide (PA ) onadenosine diphosphate (ADP)-induced rabbit platelet aggregation and thromboxane B2 (TXB2) production invitro. PA 8. 5--544. 0 μ...
关键词:PROCAINAMIDE adenosine diphosphate (ADP) platelet aggregation thromboxane B_2 (TXB_2 ) 
Inhibitiory effects of procainamide on rabbit platelet aggregation and thromboxane B_2 production in vitro被引量:2
《中国药理学报》1998年第2期164-166,共3页单春文 林继红 金云海 
目的:研究普鲁卡因胺(PA)对凝血酶诱导血小板聚集和血栓素B2(TXB2)产生的影响.方法:用比浊法和放射免疫分析法.结果:普鲁卡因胺85,34,136和544μmol·L-1有明显抑制作用.抑制率分别为45%±3...
关键词:普鲁卡因胺 血小板聚集 血栓素B2 
Procainamide inhibits A23187-induced human platelet aggregation and increase in cytosolic free-Ca2+ in the cells
《Journal of Medical Colleges of PLA(China)》1996年第4期241-243,共3页庞建新 单春文 
Effects of procainamide (PA) on human platelet aggregation and the cytosolic free-Ca2+ concentration ([Ca2+]) were investigated in vitro. PA at doses of 8.5 , 34 and 136 μmol·L-1 could inhibit the human platelet agg...
关键词:PROCAINAMIDE A23187 PLATELET AGGREGATION CYTOSOLIC free-Ca2+ 
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