Malaria continues to pose a significant global health challenge despite a significant achievement in control and elimination in certain areas.Accurate and timely diagnosis is crucial for effective disease management a...
Vascular smooth muscle cells (VSMCs) in the arterial walls play important roles in regulating vascular contraction and dilation. VSMCs actively remodel the arterial walls and dedifferentiate from the contractile to th...
supported by the National Natural Science Foundation of China(No.22273006)。
The performance of cesium lead halide per-ovskite devices is seriously affected by grain boundaries and other charge traps in the poly-crystalline perovskite thin films.LiBr doping could effectively passivate defects ...
supported by the National Natural Science Foundation of China[Grant Nos.62205367 and 62141506];Suzhou Basic Research Pilot Project[Grant Nos.SSD2023006 and SJC2021013];Jiangsu Provincial Key Research and Development Program[Grant No.BE2020664].
Super-resolution structured illumination microscopy(SR-SIM)relies heavily on post-processing reconstruction to obtain high-quality SR images from raw data.Although many SIM reconstruction algorithms have been develope...
The Extended Depth of Field(EDF)approach has been combined with Random Illumination Microscopy(RIM)to realize aberration-insensitive,fast super-resolution imaging with extended depth,which is a promising tool for dyna...
supported by the Scientific Instrument Developing Project of the Chinese Academy of Sciences(No.ZDKYYQ20220005);the National Natural Science Foundation of China(Nos.22150003,21727816,and 21721003).
The intracellular logistics system,consisting of vesicles,plays a crucial role in cellular transport.However,there is a lack of research on the types and functions of intracellular vesicles,and new technologies are ne...
received partial funding from the Air Force Office of Scientific Research(AFOSR)Award No.FA9550-20-1-0366;Office of Naval Research Award No.N00014-20-1-2184;Robert A.Welch Foundation Grant No.A-1261;received partial funding from the Air Force Office of Scientific Research(AFOSR)(FA9550-20-1-0366,FA9550-20-1-0367,FA9550-23-1-0599);the National Institutes of Health(NIH)(1R01GM127696,1R21GM142107,and 1R21CA269099);supported by the NASA,BARDA,NIH,and USFDA,under Contract/Agreement No.80ARC023CA002;support from the Consortium Research Fellows Program;performed under United States Air Force Contract No.FA8650-19-C-6024;received funding from AFOSR(17RHCOR483 and 20RHCOR051).
Measurements and imaging of the mechanical response of biological cells are critical for understanding the mechanisms of many diseases,and for fundamental studies of energy,signal and force transduction.The recent eme...
support and fruitful discussions on the project.Figure S3A was created with BioRender.com;funded by the following agencies:Agence Nationale de la Recherche(ANR-18-CE13-028,ANR-20-CE45-0024,ANR-22-CE13-0039,ANR-22-CE42-0010,ANR-22-CE42-0026);Institut Carnot star(3D-RIM);funded by the《France 2030》investment plan managed by the French National Research Agency(ANR-16-CONV-0001,ANR-21-ESRE-0002);from Excellence Initiative of Aix-Marseille University-A*MIDEX.
The ultimate aim of fluorescence microscopy is to achieve high-resolution imaging of increasingly larger biological samples.Extended depth of field presents a potential solution to accelerate imaging of large samples ...
support from the MSCA-ITN-ETN project ActiveMatter sponsored by the European Commission(Horizon 2020,Project No.812780);support from the ERC-CoG project MAPEI sponsored by the European Commission(Horizon 2020,Project No.101001267);from the Knut and AliceWallenberg Foundation(Grant No.2019.0079);aroline Beck Adiels and Giovanni Volpe acknowledge the Swedish Foundation for Strategic Research(Grant No.ITM17-0384).
Recent advancements in deep learning(DL)have propelled the virtual transformation of microscopy images across optical modalities,enabling unprecedented multimodal imaging analysis hitherto impossible.Despite these str...
supported by the National Natural Science Foundation of China(31827802,32125024,62071271,62088102,and 62222508);Shuimu Tsinghua Scholar Program(2021SM039,2022SM035);China Postdoctoral Science Foundation(BX2021159,2022M721842);Beijing Natural Science Foundation(JQ21012);the Tencent Foundation through the XPLORER PRIZE;the Youth Innovation Promotion Association of the Chinese Academy of Sciences(2020094);the New Cornerstone Science Foundation.
Detection noise significantly degrades the quality of structured illumination microscopy(SIM)images,especially under low-light conditions.Although supervised learning based denoising methods have shown prominent advan...