BLOCKERS

作品数：58被引量：241H指数：8
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相关领域：医药卫生更多>>
相关作者：董志李頔钱妍赵春景更多>>
相关机构：上海市第十人民医院安徽医科大学重庆医科大学附属第二医院重庆市生物化学与分子药理学重点实验室更多>>
相关期刊：《国际眼科杂志》《Acta Pharmacologica Sinica》《Science China Chemistry》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金广东省自然科学基金更多>>
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Ad Blockers & Online Privacy: A Comparative Analysis of Privacy Enhancing Technologies (PET)
《Journal of Software Engineering and Applications》2024年第5期378-395,共18页Siddharth M. Madikeri Vijay K. Madisetti 
Online tracking mechanisms employed by internet companies for user profiling and targeted advertising raise major privacy concerns. Despite efforts to defend against these mechanisms, they continue to evolve, renderin...
关键词：Privacy Enhancing Technology (PET) Personally Identifiable Information (PII) OpenWPM Web Privacy 
Role of renin-angiotensin system/angiotensin converting enzyme-2 mechanism and enhanced COVID-19 susceptibility in type 2 diabetes mellitus被引量：1
《World Journal of Diabetes》2024年第4期606-622,共17页Ashwin Kumar Shukla Komal Awasthi Kauser Usman Monisha Banerjee 
Coronavirus disease 2019(COVID-19)is a disease that caused a global pandemic and is caused by infection of severe acute respiratory syndrome coronavirus 2 virus.It has affected over 768 million people worldwide,result...
关键词：Angiotensin-converting enzyme 2 Angiotensin-converting enzyme inhibitors Angiotensin-II receptor blockers Complex diseases COVID-19 Type 2 diabetes 
Vonoprazan 10 mg or 20 mg vs.lansoprazole 15 mg as maintenance therapy in Asian patients with healed erosive esophagitis:A randomized controlled trial
《Chinese Medical Journal》2024年第8期962-971,共10页Yinglian Xiao Jiaming Qian Shutian Zhang Ning Dai Hoon Jai Chun Chengtang Chiu Chui Fung Chong Nobuo Funao Yuuichi Sakurai Jessica D.Eisner Li Xie Minhu Chen 
Background:Erosive esophagitis(EE)is a gastroesophageal reflux disease characterized by mucosal breaks in the esophagus.Proton pump inhibitors are widely used as maintenance therapy for EE,but many patients still rela...
关键词：Erosive esophagitis LANSOPRAZOLE Maintenance therapy Potassium-competitive acid blockers Vonoprazan 
Treatment of Helicobacter pylori with potassium competitive acid blockers:A systematic review and meta-analysis被引量：1
《World Journal of Gastroenterology》2024年第9期1213-1223,共11页Joseph Edwin Kanu Jonathan Soldera 
BACKGROUND Helicobacter pylori(H.pylori)infects over half the global population,causing gastrointestinal diseases like dyspepsia,gastritis,duodenitis,peptic ulcers,GMALT lymphoma,and gastric adenocarcinoma.Eradicating...
关键词：Helicobacter pylori infection Potassium competitive acid blockers Proton pump inhibitors Vonoprazan AMOXICILLIN 
Unlocking antitumor immunity with adenosine receptorblockers被引量：1
《Cancer Drug Resistance》2023年第4期748-767,共20页Victoria A.Remley Joel Linden Todd W.Bauer Julien Dimastromatteo 
Tumors survive by creating a tumor microenvironment(TME)that suppresses antitumor immunity.The TME suppresses the immune system by limiting antigen presentation,inhibiting lymphocyte and natural killer(NK)cell activat...
关键词：IMMUNOTHERAPY ADENOSINE adenosine receptors adenosine A2A receptors(A2AR) adenosine A2B receptors(A2BR) tumor cells immune cells tumor microenvironment 
Antihypertensive prescribing patterns in non-dialysis dependent chronic kidney disease:Findings from the Salford Kidney Study
《World Journal of Nephrology》2023年第5期168-181,共14页Rajkumar Chinnadurai Henry H L Wu Jones Abuomar Sharmilee Rengarajan David I New Darren Green Philip A Kalra 
the National Institute of Health Research Manchester Biomedical Research Centre for their funding support in the SKS(NIHR203308).
BACKGROUND Hypertension is commonly observed in patients living with chronic kidney disease(CKD).Finding an optimal treatment regime remains challenging due to the complex bidirectional cause-and-effect relationship b...
关键词：HYPERTENSION Chronic kidney disease Antihypertensive agents Prescribing patterns Cardiovascular complications Renin angiotensin system blockers 
Potassium-competitive acid blockers and gastroesophageal reflux disease被引量：8
《World Journal of Gastroenterology》2022年第28期3608-3619,共12页Wattana Leowattana Tawithep Leowattana 
Proton pump inhibitors(PPIs),the most commonly used antisecretory medications in the management of reflux illness,virtually eliminate elective surgery for ulcer disease,and relegate anti-reflux surgery to patients wit...
关键词：Potassium-competitive acid blocker Gastroesophageal reflux disease Proton pump inhibitors Treatment outcome Proton pump inhibitor-refractory patients Esophageal mucosal resistance 
Renin-angiotensin system blockers-SGLT2 inhibitorsmineralocorticoid receptor antagonists in diabetic kidney disease:A tale of the past two decades!被引量：1
《World Journal of Diabetes》2022年第7期471-481,共11页Awadhesh Kumar Singh Ritu Singh 
Several pharmacological agents to prevent the progression of diabetic kidney disease(DKD)have been tested in patients with type 2 diabetes mellitus(T2DM)in the past two decades.With the exception of renin-angiotensin ...
关键词：Renin-angiotensin system blockers SGLT-2 inhibitors Mineralocorticoid receptor antagonist Diabetic kidney disease Chronic kidney disease Renal outcomes Cardiovascular outcomes 
Non‐hemodynamic effects:Repurposing of nonselective beta‐blockers in cirrhosis?被引量：4
《Portal Hypertension & Cirrhosis》2022年第2期153-156,共4页Yi Yang Mingkai Li Jinni Luo Hongsheng Yu Hong Tian Xing Wang 
supported by grants from the National Natural Science Foundation of China(No.82070574).
To the Editor:Liver cirrhosis(LC),the end‐stage condition of chronic liver disease,results in>1,300,000 annual deaths worldwide.Meanwhile,the global incidence of decompensated cirrhosis is rising yearly.1 Following c...
关键词：CIRRHOSIS BLEEDING HYPERTENSIVE 
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein被引量：1
《Acta Pharmacologica Sinica》2022年第4期788-796,共9页Lin Wang Yan Wu Sheng Yao Huan Ge Ya Zhu Kun Chen Wen-zhang Chen Yi Zhang Wei Zhu Hong-yang Wang Yu Guo Pei-xiang Ma Peng-xuan Ren Xiang-lei Zhang Hui-qiong Li Mohammad A.Ali Wen-qing Xu Hua-liang Jiang Lei-ke Zhang Li-li Zhu Yang Ye Wei-juan Shang Fang Bai 
This work was supported by the Science and Technology Commission of Shanghai Municipality grants(Grant IDs:20431900102,20431900100,20430780300,21920102003 and 2043190012);the National Science and Technology Major Project“Key New Drug Creation and Manufacturing Program”,China(Grant ID:2018ZX09711002);National Natural Science Foundation of China(No.21920102003);Shanghai Science and Technology Development Funds(Grant ID:20QA1406400);the Youth Innovation Promotion Association CAS(grants 2018367 to LKZ);as well as the startup package from ShanghaiTech University.
An epidemic of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading worldwide. SARS-CoV-2 relies on its spike protein to invade host cells by interacting with the human recepto...
关键词：SARS-CoV-2 natural products virtual screening spike protein protein-protein interaction modulators 
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