两种阿魏酸酰胺类物质的合成及抗氧化性能研究  

Synthesis of two types of ferulic acid amides and their antioxidant properties

作　　者：高亮 张晋芳[1] 黄雅祺 王小三[1] 黄健花[1] GAO Liang;ZHANG Jinfang;HUANG Yaqi;WANG Xiaosan;HUANG Jianhua(Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province,State Key Laboratory of Food Science and Technology,School of Food Science and Technology,Jiangnan University,Wuxi 214122,Jiangsu,China)

机构地区：[1]江南大学食品学院,食品科学与技术国家重点实验室,食品安全与质量控制协同创新中心,江苏无锡214122

出　　处：《中国油脂》2021年第3期22-27,共6页China Oils and Fats

基　　金：国家自然科学基金资助项目(31701559,31972035)。

摘　　要：以阿魏酸为原料,采用化学法合成了阿魏酸苯乙酰胺和阿魏酸酪酰胺两种抗氧化剂,采用液质联用和核磁共振氢谱对产物进行定性,采用高效液相色谱进行定量分析。另外,将合成的两种抗氧化剂与其他8种抗氧化剂的抗煎炸大豆油氧化效果进行比较。结果表明:两种产物阿魏酸苯乙酰胺、阿魏酸酪酰胺纯度分别为97.05%和94.55%;两种阿魏酸酰胺类物质具有较强的抗氧化能力,抗氧化能力均优于迷迭香提取物、谷维素、BHT、混合生育酚和茶多酚棕榈酸酯。Two antioxidants feruloylphenethylamine (FPA) and feruloyltyramine (FTA) were synthesized from ferulic acid by chemical method. The product was characterized by liquid chromatography-mass spectrometry and nuclear magnetic resonance hydrogen spectroscopy,and quantified by high performance liquid chromatography. The antioxidant effects of the two synthesized antioxidants were compared with other eight antioxidants. The results showed that the purity of FPA and FTA were 97. 05% and 94. 55%,respectively. The two types of ferulic acid amides had excellent antioxidant capacity,which were superior to rosemary extract,oryzanol,BHT,tocopherols and tea polyphenol palmitate.

关 键 词：阿魏酸 阿魏酸苯乙酰胺 阿魏酸酪酰胺 抗氧化剂 

分 类 号：R914[医药卫生—药物化学] R96[医药卫生—药学]