Compensation for Neurodegeneration by Hippocampal Neurogenesis in Alzheimer’s Disease: Where is the way?  

作　　者：Jie Zheng Yawen Li 

机构地区：[1]Department of Pharmacology,Key Laboratory of Basic Pharmacology of Ministry of Education,Joint International Research Laboratory of Ethnomedicine of Ministry of Education,Key Laboratory of Basic Pharmacology of Guizhou Province,Zunyi Medical University,Zunyi 563000,China [2]Digestive Disease Institute of Guizhou Province,Clinical Medical Research Center of Digestive Diseases of Guizhou Province,Department of Gastroenterology,Affiliated Hospital of Zunyi Medical University,Zunyi 563000,China

出　　处：《Neuroscience Bulletin》2021年第6期885-888,共4页神经科学通报（英文版）

基　　金：This insight article was supported by the National Natural Science Foundation of China(81901107);the China Postdoctoral Science Foundation(2018M632872).

摘　　要：Neurodegeneration,a defining hallmark of Alzheimer's disease(AD),features the progressive loss of neuronal structure and functions.Therapeutic approaches to AD show limited efficiency in halting the neurodegeneration to date.Given the lack of neuronal renewability in most subareas of the adult brain,symptomatic drugs or treatments cannot repopulate neurons and rewire the degenerated neuronal circuits in AD.

关 键 词：DEGENERATION ALZHEIMER DRUGS 

分 类 号：R749.16[医药卫生—神经病学与精神病学]