Therapeutic Applications of Naringenin, a Flavanone Enriched in Citrus Fruits, for Disorders beyond Diabetes  

作　　者：Jaswinder Kaur Manish Vyas Joginder Singh Ram Prasad Jeena Gupta 

机构地区：[1]School of Bioengineering and Biosciences,Lovely Professional University,Phagwara,Punjab,144411,India [2]School of Pharmaceutical Sciences,Lovely Professional University,Phagwara,Punjab,144411,India [3]Department of Botany,Mahatma Gandhi Central University,Motihari,Bihar,845801,India

出　　处：《Phyton-International Journal of Experimental Botany》2020年第4期795-803,共9页国际实验植物学杂志（英文）

摘　　要：In recent years,there has been an increase in epidemiological studies to highlight the health benefits of plant secondary metabolites.Flavonoids(polyphenolic plant secondary metabolites)are recently emerging as an important source for the discovery of new drugs increasing their pharmaceuticals,nutraceutical and medicinal applications.Naringenin is a flavanone,enriched in citrus fruits,tomatoes,bergamot,etc.which has been evaluated extensively for managing diabetes.However,in addition to this,naringenin had been ascribed to various important biological activities like antioxidant,antiviral,anticancer,anti-inflammatory,antiestrogenic,etc.This article aims at highlighting the therapeutic value of naringenin in managing disorders other than diabetes and its role in regulating gene expression by altering chromatin structure as histone deacetylase inhibitor.The understanding of these phenomena will increase the overall knowledge of the various health-promoting effects of citrus fruits.

关 键 词：NARINGENIN FLAVANONE ANTI-VIRAL HEPATOPROTECTIVE ANTI-CANCER anti-estrogenic 

分 类 号：O62[理学—有机化学]