生物活性肽和肠道菌群相互作用研究进展  

Research progress on interaction between bioactive peptides and gut microbiota

作　　者：陈心瑷 翟兴月[2] 佟长青 赵菲 李伟 CHEN Xin-Ai;ZHAI Xing-Yue;TONG Chang-Qing;ZHAO Fei;LI Wei(College of Food Science and Engineering,Dalian Ocean University,Dalian 116023,China;Clinical Nutrition Department,the Second Hospital of Dalian Medical University,Dalian 116023,China;Changsha Jinchi Biotech Co.,Ltd.,Changsha 410000,China)

机构地区：[1]大连海洋大学食品科学与工程学院,大连116023 [2]大连医科大学附属第二医院临床营养科,大连116023 [3]长沙金驰生物科技有限公司,长沙410000

出　　处：《食品安全质量检测学报》2022年第4期1044-1049,共6页Journal of Food Safety and Quality

基　　金：湖南省战略性新兴产业科技攻关与重大科技成果转化项目(2013GK4100)。

摘　　要：生物活性肽是对生物机体的生命活动具有积极作用的肽类化合物,近年来逐渐成为食品、保健食品以及特殊医学用食品等领域的研究热点之一。研究表明,肠道中微生物产生的蛋白酶作用于食物中的蛋白质,可以产生生物活性肽。另一方面,生物活性肽对肠道菌群的结构具有明显的调节作用,而肠道菌群结构的改变对宿主的健康产生重要的影响。本文对生物活性肽与肠道菌群的相互作用、基于调节肠道菌群而发挥各种显效的作用以及研究生物活性肽与肠道菌群作用的技术手段等内容进行综述,以期为深入研究生物活性肽对人体健康作用的机制提供参考。Bioactive peptides are peptides that play a positive role in the life activities of organisms. In recent years, bioactive peptides have become one of research hotspots in the fields of food, health food and special medical food. Many researchers have discovered that proteases secreted by gut microbiota digest proteins in food and can produce bioactive peptides. On the other hand, bioactive peptides can significantly regulate the scale of intestinal flora, and the change of intestinal flora scale has an important impact on the health of the host. This paper reviewed the interaction between bioactive peptides and intestinal flora, various effective effects based on regulating intestinal flora, and the technical means to investigate the interaction between bioactive peptides and intestinal flora, in order to provide reference for the further study of the mechanism of bioactive peptides on human health.

关 键 词：生物活性肽 肠道菌群 相互作用 

分 类 号：TS201.3[轻工技术与工程—食品科学] TS201.2[轻工技术与工程—食品科学与工程]