谷物蛋白及多肽调控2型糖尿病靶点研究进展  

Progress in the Study of the Role of Grain Proteins and Peptides in Regulating the Therapeutic Targets for Type 2 Diabetes

作　　者：王晗 侯殿志 付永霞 赵卿宇 沈群[1] WANG Han;HOU Dianzhi;FU Yongxia;ZHAO Qingyu;SHEN Qun(National Center of Technology Innovation(Deep Processing of Highland Barley)in Food Industry,National Engineering Research Center for Fruits and Vegetables Processing,College of Food Science&Nutritional Engineering,China Agricultural University,Beijing 100083,China)

机构地区：[1]中国农业大学食品科学与营养工程学院,国家粮食产业(青稞深加工)技术创新中心,国家果蔬加工工程技术研究中心,北京100083

出　　处：《食品科学》2022年第9期310-316,共7页Food Science

基　　金：国家现代农业产业技术体系(CARS-06-14.5)。

摘　　要：近年来,许多研究表明谷物蛋白及其被酶水解后获得的小分子肽(包括二肽基肽酶-4(dipeptidyl peptidase-4,DPP-IV)、胰高血糖素样肽-1(glucagon-like peptide-1,GLP-1)、肽YY(peptide YY,PYY)和相关酶等)能作用于2型糖尿病(type 2 diabetes mellitus,T2DM)的治疗靶点,进而改善T2DM。本文在总结国内外有关谷物蛋白和多肽对糖尿病作用研究的基础上,对其未来在防治T2DM上的发展前景进行了展望。In recent years,numerous studies have demonstrated that grain proteins and peptides derived from their enzymatic hydrolysis such as dipeptidyl peptidase-4(DPP-IV),glucagon-like peptide-1(GLP-1),peptide YY(PYY)and related enzymes can act on the therapeutic targets for type 2 diabetes mellitus(T2DM)and thereby improve T2DM.This article gives a summary of recent research on the beneficial effect of grain proteins and peptides on T2DM,and discusses future prospects for the application of grain proteins and peptides in T2DM treatment.

关 键 词：谷物 蛋白 多肽 2型糖尿病 

分 类 号：TS201.4[轻工技术与工程—食品科学]