灵芝液态发酵胞内外多糖的研究进展  

Liquid fermentation of Ganoderma lingzhi for intracellular and extracellular polysaccharides:a review

作　　者：郭嘉 冯杰[1] 谭贻[1] 唐传红 刘艳芳[1] 周帅[1] 张劲松[1] GUO Jia;FENG Jie;TAN Yi;TANG Chuanhong;LIU Yanfang;ZHOU Shuai;ZHANG Jinsong(Key Laboratory of Edible Fungi Resources and Utilization(South),Ministry of Agriculture and Rural Affairs,National Engineering Research Center of Edible Fungi,Institute of Edible Fungi,Shanghai Academy of Agricultural Sciences,Shanghai 201403,China;School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China)

机构地区：[1]上海市农业科学院食用菌研究所国家食用菌工程技术研究中心农业农村部南方食用菌资源利用重点实验室,上海201403 [2]上海理工大学健康科学与工程学院,上海200093

出　　处：《微生物学通报》2022年第10期4337-4356,共20页Microbiology China

基　　金：上海市现代农业产业技术体系(沪农科产字[2022]第9号);上海市农业科学院卓越团队建设计划(2022A-03);上海人才发展资金(2019052);上海市农业科学院攀高计划。

摘　　要：灵芝具有悠久的药用历史,其活性物质灵芝多糖具有广泛的药理活性,利用液态发酵技术获取灵芝多糖展现出独特优势。近年来,关于灵芝多糖液态发酵的研究报道越来越多,引起了研究者的广泛关注。本文从灵芝多糖的生物合成代谢及调控、液态发酵的培养基及工艺优化等方面对近期的研究结果进行总结,以期为灵芝液态发酵制备胞内外多糖及其产业化应用提供参考和依据。Ganoderma lingzhi has long been used as medicine and the active components polysaccharides have extensive pharmacological activities.Liquid fermentation shows unique advantages in extracting G.lingzhi polysaccharides.In recent years,there has been an explosion of research on the liquid fermentation of G.lingzhi to yield polysaccharides,and this technology has attracted the interest of scholars.We summarized the research on the biosynthesis and biosynthesis regulation of G.lingzhi polysaccharides,the optimization of the medium for and process of liquid fermentation,among others,hoping to provide a reference and basis for liquid fermentation of G.lingzhi to yield intracellular and extracellular polysaccharides and its industrial application.

关 键 词：灵芝 液态发酵 生物合成 胞内多糖 胞外多糖 

分 类 号：TQ929.2[轻工技术与工程—发酵工程]