噬菌体在动物源性食品致病菌控制中的应用  

Research Progress on the Application of Bacteriophage in the Control of Pathogenic Bacteria in Animal-Derived Food

作　　者：聂长丽 张明 董浩 宋钢 张国清 郭晓华 申照华 张德福 励建荣 NIE Changli;ZHANG Ming;DONG Hao;SONG Gang;ZHANG Guoqing;GUO Xiaohua;SHEN Zhaohua;ZHANG Defu;LI Jianrong(College of Food Science and Engineering,Institute of Oceanography,Bohai University,National and Local Joint Engineering Research Center of Fresh Agricultural Products Storage,Processing and Safety Control Technology,Jinzhou 121013,China;Shandong Meijia Group Co.LTD,Rizhao 276806,China;Linghai Dalian Marine Treasures Breeding Co.LTD,Jinzhou 121211,China;Jinzhou Longhaixingang Science and Technology Co.Ltd.,Jinzhou 121211,China;Jinzhou Agricultural and Rural Comprehensive Service Center Aquatic Technology Extension Station,Jinzhou 121000,China)

机构地区：[1]渤海大学食品科学与工程学院,渤海大学海洋研究院,生鲜农产品贮藏加工及安全控制技术国家地方联合工程研究中心,辽宁锦州121013 [2]山东美佳集团有限公司,山东日照276806 [3]凌海市达莲海珍品养殖有限责任公司,辽宁锦州121211 [4]锦州市龙海馨港科技有限公司,辽宁锦州121211 [5]锦州市农业农村综合服务中心水产技术推广总站,辽宁锦州ꎬ121000

出　　处：《中国渔业质量与标准》2022年第5期39-50,共12页Chinese Fishery Quality and Standards

基　　金：国家自然科学基金项目(31801662);国家重点研发计划项目(2019YFD0901702)。

摘　　要：近些年来,随着全球范围内耐药性细菌的出现,需要开发新的天然杀菌剂解决这一问题。噬菌体作为抗菌药物的替代品已经广泛应用于家禽、家畜及水产养殖中,以防控动物源性食品中的病原菌。本研究就应用噬菌体对动物源性食品中致病菌防控的研究进展、噬菌体治疗的优势及面临的挑战等几方面进行综述,为噬菌体制剂在动物源性食品病原菌防控方面的研究及应用提供参考。In recent years,with the emergence of drug-resistant pathogens all over the world,it is necessary to develop new antibacterial substitutes to solve this problem.Bacteriophage has served as an alternative to antibiotics in poultry and aquaculture animals for the purpose of controlling bacterial pathogens in animal-derived food.This review summarizes the general situation of bacteriophages,research progress of the application of bacteriophage in the prevention and control of pathogenic bacteria in animal-derived food,advantages and challenges of bacteriophage therapy with the aim of providing reference for research and application of bacteriophage preparations in the prevention and control of pathogenic bacteria in animal-derived food.

关 键 词：噬菌体 噬菌体治疗 食源性致病菌 动物性食品 食品安全 

分 类 号：TS254.1[轻工技术与工程—水产品加工及贮藏工程]