基于色谱-质谱联用技术的食品中农药残留高通量非靶向检测技术研究进展  

Progress in High-Throughput and Non-targeted Detection of Pesticide Residues in Foods by Chromatography-Mass Spectrometry

作　　者：黎才婷 雷紫依 丁胜华[2] 蒋立文[1] 刘霞[1] 李跑 LI Caiting;LEI Ziyi;DING Shenghua;JIANG Liwen;LIU Xia;LI Pao(Hunan Provincial Key Laboratory of Food Science and Biotechnology,College of Food Science and Technology,Hunan Agricultural University,Changsha 410128,China;Hunan Agricultural Product Processing Institute,Hunan Academy of Agricultural Sciences,Changsha 410125,China)

机构地区：[1]湖南农业大学食品科学技术学院,食品科学与生物技术湖南省重点实验室,湖南长沙410128 [2]湖南省农业科学院,湖南省农产品加工研究所,湖南长沙410125

出　　处：《食品科学》2023年第5期231-240,共10页Food Science

基　　金：国家自然科学基金青年科学基金项目(31601551);中国博士后科学基金面上项目(2019M650187);湖南省教育厅科学研究项目重点项目(21A0127)。

摘　　要：农药残留导致的食品安全事件威胁人们的健康和生命。现阶段食品中的农药残留具有品类多、残留量低且施用未知等特点,检测难度较大。因此,开发食品中农药残留高通量非靶向检测技术具有重要意义。色谱-质谱联用技术因具有高分离、高鉴别、高通量、非靶向等优点,在农药残留检测领域得到了广泛应用。本文对近10年国内外基于色谱-质谱联用技术的食品中农药残留高通量非靶向检测相关报道进行归纳和总结,简要介绍食品中多农药残留检测的现状,重点从多维色谱及高分辨质谱技术的开发、吸附材料及样品前处理技术的改进、化学计量学方法的优化等方面阐述色谱-质谱联用技术在食品中农药残留检测中的应用进展,并对其存在的问题提出相关建议,以期为色谱-质谱联用技术在食品中多农药残留检测领域的相关研究应用提供新的参考依据。Food safety incidents caused by pesticide residues are threatening the life and health of people.At present,pesticide residues in food samples are miscellaneous,low and unknown to testing personnel and thus difficult to detect.Therefore,it is of great significance to develop high-throughput and non-targeted for the detection of pesticide residues in food samples.Chromatography-mass spectrometry has been widely used in the field of pesticide residue detection because of its advantages of high separation and identification efficiency as well as high-throughput and non-targeted nature.This paper summarizes the literature on high-throughput and non-targeted detection of pesticide residues in food samples by chromatography-mass spectrometry in the past 10 years.The current status of multi-pesticide residue detection in food samples is briefly described.Besides,this paper focuses on the application of chromatography-mass spectrometry in the detection of pesticide residues in food samples from the perspectives of the development of multidimensional chromatography and high-resolution mass spectrometry,the improvement of sorbent materials and sample pretreatment techniques,and the optimization of chemometric algorithms.Some suggestions for the problems existing in this field of research are put forward aiming to provide a new reference for the application of chromatography-mass spectrometry in the detection of multi-pesticide residues in food samples.

关 键 词：多农药残留 色谱-质谱联用技术 高通量 非靶向 样品前处理 化学计量学 

分 类 号：TS207.3[轻工技术与工程—食品科学]