茶多酚对高脂饮食诱导的非酒精性脂肪性肝病预防作用的研究进展  

Progress in Research on the Preventive Effect of Tea Polyphenols on Non-alcoholic Fatty Liver Disease Induced by High-Fat Diet

作　　者：金璨 邓颖 曹楠 张晓丽 肖长义[1,2,3] 何建刚 何功威 李世刚 JIN Can;DENG Ying;CAO Nan;ZHANG Xiaoli;XIAO Changyi;HE Jiangang;HE Gongwei;LI Shigang(Medical College of China Three Gorges University,Yichang 443000,China;Third-grade Pharmacological Laboratory on Traditional Chinese Medicine Approved by State Administration of Traditional Chinese Medicine,China Three Gorges University,Yichang 443000,China;Hubei Changshengchuan Chin-brick Tea Research Institute,Yichang 443000,China)

机构地区：[1]三峡大学医学院,湖北宜昌443000 [2]三峡大学国家中医药管理局中药药理(肿瘤)科研三级实验室,湖北宜昌443000 [3]湖北长盛川青砖茶研究所,湖北宜昌443000

出　　处：《食品科学》2023年第7期295-302,共8页Food Science

基　　金：国家自然科学基金面上项目(81673665,81274166);湖北省区域创新发展科技专项(2020BGC015);宜昌市科技研究与开发项目(A21-1-075)。

摘　　要：随着饮食习惯的改变和生活水平的提高,特别是高脂饮食的大量摄入,非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)发病率正在逐渐升高,西方发达国家平均发病率为20%~30%,我国平均发病率为15%~30%。NAFLD已经成为全球主要的公共卫生问题之一,严重威胁着人类的健康,其临床治疗仍然是一个挑战。茶多酚是从茶叶中提取出来的一种活性物质,其对人体健康有一定益处,特别是在一些常见疾病的预防作用方面具有较大潜力。为进一步系统了解茶多酚对NAFLD的作用,本文对茶多酚预防高脂饮食诱导的NAFLD的研究进展进行总结。With the change of dietary habits and the improvement of living standards,especially high fat intake,the incidence of non-alcoholic fatty liver disease(NAFLD) is gradually increasing,with an average incidence of 20%–30% in western developed countries and 15%–30% in China.NAFLD has become one of the major global public health problems posing a serious threat to human health,and its clinical treatment remains a challenge.Tea polyphenols are bioactive substances extracted from tea leaves,which have health benefits in particular preventing some common diseases.To further understand the effects of tea polyphenols on NAFLD systematically,this article summarizes recent progress in research on the preventive effect of tea polyphenols on high-fat diet-induced NAFLD.

关 键 词：茶多酚 高脂饮食 非酒精性脂肪性肝病 预防作用 新靶点 

分 类 号：TS201.4[轻工技术与工程—食品科学]