The Memory Orchestra:Contribution of Astrocytes  

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作  者:Yi-Hua Chen Shi-Yang Jin Jian-Ming Yang Tian-Ming Gao 

机构地区:[1]State Key Laboratory of Organ Failure Research,Key Laboratory of Mental Health of the Ministry of Education,Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence,Guangdong Province Key Laboratory of Psychiatric Disorders,Department of Neurobiology,School of Basic Medical Sciences,Southern Medical University,Guangzhou 510515,China

出  处:《Neuroscience Bulletin》2023年第3期409-424,共16页神经科学通报(英文版)

基  金:supported by grants from the STI2030-Major Projects(2022ZD0204702;2022ZD0214300);the National Natural Science Foundation of China(82090032,31830033,and 32271014);the Key Area Research and Development Program of Guangdong Province(2018B030334001 and 2018B030340001);the Science and Technology Program of Guangzhou(202007030013).

摘  要:For decades,memory research has centered on the role of neurons,which do not function in isolation.However,astrocytes play important roles in regulating neuronal recruitment and function at the local and network levels,forming the basis for information processing as well as memory formation and storage.In this review,we discuss the role of astrocytes in memory functions and their cellular underpinnings at multiple time points.We summarize important breakthroughs and controversies in the field as well as potential avenues to further illuminate the role of astrocytes in memory processes.

关 键 词:ASTROCYTES Learning and memory GPCR Calcium signal PLASTICITY 

分 类 号:R749.4[医药卫生—神经病学与精神病学]

 

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