Three‐dimensional magnetic resonance elastography in chronic liver disease  

作　　者：Chunli Li He Zhu Yan Wang Ye Gu Yu Shi 

机构地区：[1]Department of Radiology,Shengjing Hospital of China Medical University,Shenyang,Liaoning,China [2]The Intervention Department,The Sixth People's Hospital of Shenyang,Shenyang,Liaoning,China [3]Department of Infectious Disease,The Sixth People's Hospital of Shenyang,Shenyang,Liaoning,China

出　　处：《Portal Hypertension & Cirrhosis》2023年第1期32-39,共8页门静脉高压与肝硬化（英文）

基　　金：National Natural Science Foundation of China,Grant/Award Number:82071805;National Youth Talent Support Program;Innovation Talent Program in Sciences and Technologies for Young and Middle‐aged Scientists of Shenyang,Grant/Award Number:RC210265。

摘　　要：Chronic liver disease(CLD)has become a major health problem worldwide owing to its increased morbidity and mortality.Evaluation of the degree of liver injury is crucial for the clinical management and treatment of CLD patients.In the current clinical practice,liver biopsy with histological analysis is the clinical standard for assessing the degree of CLD injury.However,liver biopsy is an invasive procedure that is limited by sampling errors and interobserver variability and is insufficient for screening and monitoring.Advanced three‐dimensional magnetic resonance elastography(3D MRE)is a simple,fast,safe,and noninvasive technology.This offers comprehensive insight into increased liver stiffness beyond stage‐specific fibrosis.This technology exhibits considerable potential for comprehensively and simultaneously assessing early necroinflammation,discriminating necroinflammation from fibrosis,detecting nonalcoholic steatohepatitis severity,predicting cirrhosis complications,and identifying tumor recurrence.Nevertheless,the clinical application and promotion of this technology are currently required in China.3D MRE should evolve towards better clinical convenience and satisfaction to provide an imaging basis to improve treatment selection in CLD patients and facilitate its widespread use.

关 键 词：3D MRE chronic liver disease CIRRHOSIS FIBROSIS INFLAMMATION tumor recurrence 

分 类 号：R57[医药卫生—消化系统]