The role of targeting protein for Xklp2 in tumorigenesis of hepatocellular carcinoma  

作　　者：Ting Li Lu-Jian Zhu An-Min Huang Yi-Feng Wei Jun Xu Ye-Jin Xu 

机构地区：[1]Department of Infectious Diseases,Jinhua Municipal Central Hospital,Jinhua 321000,China [2]School of the First Clinical Medical Sciences(School of Information and Engineering),Wenzhou Medical University,Wenzhou 325035,China

出　　处：《Hepatobiliary & Pancreatic Diseases International》2023年第4期418-422,共5页国际肝胆胰疾病杂志（英文版）

基　　金：supported by a grant from Zhejiang Province Public Welfare Technology Application Research Funding Project(GD22H036691).

摘　　要：To the Editor:Hepatocellular carcinoma(HCC)is a prevalent form of gastrointestinal malignancies.The current combination of immunotherapy and other treatments improves overall survival compared to conventional therapies,but the immunosuppressive microenvironment of HCC is a significant barrier to the efficacy of immunothera-peutic drugs[1].Tumor immune escape is promoted by interactions among immunosuppressive cells,including tumor-associated macrophages,marrow-derived suppressor cells,tumor-associated neutrophils,cancer-associated fibroblasts,and tumor-infiltrating Tregs[2].

关 键 词：DRUGS SUPPRESSOR HEPATOCELLULAR 

分 类 号：R735.7[医药卫生—肿瘤]